2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide

C103H127Cl4N27O12 — CID 167707147

IUPAC2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide
SMILESCNC(=O)COc1cc2cc(Nc3nc(N4CC5C(C)C5C4)ncc3Cl)ccc2n(C(C)C)c1=O.CNC(=O)COc1cc2cc(Nc3nc(N4CCC5(CC4)CN(C)C5)ncc3Cl)ccc2n(C(C)C)c1=O.CNC(=O)COc1cc2cc(Nc3nc(N4CCC5(CCN(C)CC5)CC4)ncc3Cl)ccc2n(C(C)C)c1=O.CNC(=O)COc1cc2cc(Nc3nc(N4CCN(C)CC4)ncc3Cl)ccc2n(C)c1=O
InChIInChI=1S/C29H38ClN7O3.C27H34ClN7O3.C25H29ClN6O3.C22H26ClN7O3/c1-19(2)37-23-6-5-21(15-20(23)16-24(27(37)39)40-18-25(38)31-3)33-26-22(30)17-32-28(34-26)36-13-9-29(10-14-36)7-11-35(4)12-8-29;1-17(2)35-21-6-5-19(11-18(21)12-22(25(35)37)38-14-23(36)29-3)31-24-20(28)13-30-26(32-24)34-9-7-27(8-10-34)15-33(4)16-27;1-13(2)32-20-6-5-16(7-15(20)8-21(24(32)34)35-12-22(33)27-4)29-23-19(26)9-28-25(30-23)31-10-17-14(3)18(17)11-31;1-24-19(31)13-33-18-11-14-10-15(4-5-17(14)29(3)21(18)32)26-20-16(23)12-25-22(27-20)30-8-6-28(2)7-9-30/h5-6,15-17,19H,7-14,18H2,1-4H3,(H,31,38)(H,32,33,34);5-6,11-13,17H,7-10,14-16H2,1-4H3,(H,29,36)(H,30,31,32);5-9,13-14,17-18H,10-12H2,1-4H3,(H,27,33)(H,28,29,30);4-5,10-12H,6-9,13H2,1-3H3,(H,24,31)(H,25,26,27)
InChIKeyZGNUPJKIGZIVJC-UHFFFAOYSA-N
MW2077.14 g/mol
LogP12.83
Rot. Bonds27

About 2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide

2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide (PubChem CID 167707147) has the molecular formula C103H127Cl4N27O12 and a molecular weight of 2077.14 g/mol. Its IUPAC name is 2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide.

Molecular Properties

Compound Name2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide
PubChem CID167707147
Molecular FormulaC103H127Cl4N27O12
Molecular Weight2077.14 g/mol
Exact Mass2073.89
IUPAC Name2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide
SMILESCNC(=O)COc1cc2cc(Nc3nc(N4CC5C(C)C5C4)ncc3Cl)ccc2n(C(C)C)c1=O.CNC(=O)COc1cc2cc(Nc3nc(N4CCC5(CC4)CN(C)C5)ncc3Cl)ccc2n(C(C)C)c1=O.CNC(=O)COc1cc2cc(Nc3nc(N4CCC5(CCN(C)CC5)CC4)ncc3Cl)ccc2n(C(C)C)c1=O.CNC(=O)COc1cc2cc(Nc3nc(N4CCN(C)CC4)ncc3Cl)ccc2n(C)c1=O
InChIInChI=1S/C29H38ClN7O3.C27H34ClN7O3.C25H29ClN6O3.C22H26ClN7O3/c1-19(2)37-23-6-5-21(15-20(23)16-24(27(37)39)40-18-25(38)31-3)33-26-22(30)17-32-28(34-26)36-13-9-29(10-14-36)7-11-35(4)12-8-29;1-17(2)35-21-6-5-19(11-18(21)12-22(25(35)37)38-14-23(36)29-3)31-24-20(28)13-30-26(32-24)34-9-7-27(8-10-34)15-33(4)16-27;1-13(2)32-20-6-5-16(7-15(20)8-21(24(32)34)35-12-22(33)27-4)29-23-19(26)9-28-25(30-23)31-10-17-14(3)18(17)11-31;1-24-19(31)13-33-18-11-14-10-15(4-5-17(14)29(3)21(18)32)26-20-16(23)12-25-22(27-20)30-8-6-28(2)7-9-30/h5-6,15-17,19H,7-14,18H2,1-4H3,(H,31,38)(H,32,33,34);5-6,11-13,17H,7-10,14-16H2,1-4H3,(H,29,36)(H,30,31,32);5-9,13-14,17-18H,10-12H2,1-4H3,(H,27,33)(H,28,29,30);4-5,10-12H,6-9,13H2,1-3H3,(H,24,31)(H,25,26,27)
InChIKeyZGNUPJKIGZIVJC-UHFFFAOYSA-N
XLogP12.83
TPSA415.24 Ų
H-Bond Donors8
H-Bond Acceptors35
Rotatable Bonds27
Heavy Atoms146
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002077.14
LogP ≤ 512.83
H-Bond Donors ≤ 58
H-Bond Acceptors ≤ 1035

Analyze 2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide with MolForge

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Related Compounds

6-[[5-chloro-2-(2-methyl-2,8-diazaspiro[4.5]decan-8-yl)pyrimidin-4-yl]amino]-3-(2-oxobutoxy)-1-propan-2-ylquinolin-2-one;6-[[5-chloro-2-(8-methyl-2,8-diazaspiro[4.5]decan-2-yl)pyrimidin-4-yl]amino]-3-(2-oxobutoxy)-1-propan-2-ylquinolin-2-one;6-[[5-chloro-2-(2-methyl-2,6-diazaspiro[3.4]octan-6-yl)pyrimidin-4-yl]amino]-3-(2-oxobutoxy)-1-propan-2-ylquinolin-2-one;6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-3-(2-oxobutoxy)-1-propan-2-ylquinolin-2-one
CID 167576530
1-[5-chloro-4-[[3-[2-(methylamino)-2-oxoethoxy]-2-oxo-1-propan-2-ylquinolin-6-yl]amino]pyrimidin-2-yl]piperidine-4-carboxylic acid
CID 135137768
2-[6-[[5-chloro-2-[(3R,5S)-4,4-difluoro-3,5-dimethylpiperidin-1-yl]pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide
CID 142606275
2-[6-[[5-chloro-2-[(5R)-3,5-dimethylpiperidin-1-yl]pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide
CID 135137908
2-[6-[[5-chloro-2-[(2S)-2-methylmorpholin-4-yl]pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide
CID 165380040
2-[6-[[5-chloro-2-[4-hydroxy-4-(trifluoromethyl)piperidin-1-yl]pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide
CID 135137636
1-[5-chloro-4-[[3-[2-(methylamino)-2-oxoethoxy]-2-oxo-1-propan-2-ylquinolin-6-yl]amino]pyrimidin-2-yl]-N,N-dimethylpiperidine-4-carboxamide
CID 135137797
2-[6-[[5-chloro-2-(4-cyclohexyloxypiperidin-1-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide
CID 171846904
2-[6-[[5-chloro-2-[4-(4-methylpiperidin-1-yl)piperidin-1-yl]pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide
CID 135137496
2-[6-[[2-[(3R,5S)-3-(2-aminoethyl)-4,4-difluoro-5-methylpiperidin-1-yl]-5-chloropyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide
CID 171525960
2-[6-[[5-chloro-2-(2-ethylmorpholin-4-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;ethane
CID 156729628
2-[6-[[5-chloro-2-[4-[2-(dimethylamino)ethyl]piperazin-1-yl]pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide
CID 135137929

Frequently Asked Questions

What is the IUPAC name of 2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide?
The IUPAC name of 2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide (CID 167707147) is 2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide.
What is the SMILES notation for 2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide?
The canonical SMILES for 2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide is CNC(=O)COc1cc2cc(Nc3nc(N4CC5C(C)C5C4)ncc3Cl)ccc2n(C(C)C)c1=O.CNC(=O)COc1cc2cc(Nc3nc(N4CCC5(CC4)CN(C)C5)ncc3Cl)ccc2n(C(C)C)c1=O.CNC(=O)COc1cc2cc(Nc3nc(N4CCC5(CCN(C)CC5)CC4)ncc3Cl)ccc2n(C(C)C)c1=O.CNC(=O)COc1cc2cc(Nc3nc(N4CCN(C)CC4)ncc3Cl)ccc2n(C)c1=O.
What is the InChIKey of 2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide?
The InChIKey is ZGNUPJKIGZIVJC-UHFFFAOYSA-N. The full InChI is InChI=1S/C29H38ClN7O3.C27H34ClN7O3.C25H29ClN6O3.C22H26ClN7O3/c1-19(2)37-23-6-5-21(15-20(23)16-24(27(37)39)40-18-25(38)31-3)33-26-22(30)17-32-28(34-26)36-13-9-29(10-14-36)7-11-35(4)12-8-29;1-17(2)35-21-6-5-19(11-18(21)12-22(25(35)37)38-14-23(36)29-3)31-24-20(28)13-30-26(32-24)34-9-7-27(8-10-34)15-33(4)16-27;1-13(2)32-20-6-5-16(7-15(20)8-21(24(32)34)35-12-22(33)27-4)29-23-19(26)9-28-25(30-23)31-10-17-14(3)18(17)11-31;1-24-19(31)13-33-18-11-14-10-15(4-5-17(14)29(3)21(18)32)26-20-16(23)12-25-22(27-20)30-8-6-28(2)7-9-30/h5-6,15-17,19H,7-14,18H2,1-4H3,(H,31,38)(H,32,33,34);5-6,11-13,17H,7-10,14-16H2,1-4H3,(H,29,36)(H,30,31,32);5-9,13-14,17-18H,10-12H2,1-4H3,(H,27,33)(H,28,29,30);4-5,10-12H,6-9,13H2,1-3H3,(H,24,31)(H,25,26,27).
What are the key properties of 2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide?
2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide has a molecular weight of 2077.14 g/mol, XLogP of 12.83, 27 rotatable bonds, 8 hydrogen bond donors, and 35 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[6-[[5-chloro-2-(6-methyl-3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)pyrimidin-4-yl]amino]-2-oxo-1-propan-2-ylquinolin-3-yl]oxy-N-methylacetamide;2-[6-[[5-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1-methyl-2-oxoquinolin-3-yl]oxy-N-methylacetamide is sourced from PubChem (CID 167707147), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).