About N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide
N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide (PubChem CID 168509938) has the molecular formula C18H17N5O2S
and a molecular weight of 367.43 g/mol. Its IUPAC name is N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide.
Molecular Properties
| Compound Name | N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide |
| PubChem CID | 168509938 |
| Molecular Formula | C18H17N5O2S |
| Molecular Weight | 367.43 g/mol |
| Exact Mass | 367.11 |
| IUPAC Name | N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide |
| SMILES | N#Cc1ccc(-c2ccc(C(=O)N[C@H](CN)c3nc(CO)cs3)[nH]2)cc1 |
| InChI | InChI=1S/C18H17N5O2S/c19-7-11-1-3-12(4-2-11)14-5-6-15(22-14)17(25)23-16(8-20)18-21-13(9-24)10-26-18/h1-6,10,16,22,24H,8-9,20H2,(H,23,25)/t16-/m1/s1 |
| InChIKey | VMKFFJDLKSXFGN-MRXNPFEDSA-N |
| XLogP | 1.93 |
| TPSA | 127.82 Ų |
| H-Bond Donors | 4 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 26 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 367.43 |
| LogP ≤ 5 | 1.93 |
| H-Bond Donors ≤ 5 | 4 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide?
The IUPAC name of N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide (CID 168509938) is N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide.
What is the SMILES notation for N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide?
The canonical SMILES for N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide is N#Cc1ccc(-c2ccc(C(=O)N[C@H](CN)c3nc(CO)cs3)[nH]2)cc1.
What is the InChIKey of N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide?
The InChIKey is VMKFFJDLKSXFGN-MRXNPFEDSA-N. The full InChI is InChI=1S/C18H17N5O2S/c19-7-11-1-3-12(4-2-11)14-5-6-15(22-14)17(25)23-16(8-20)18-21-13(9-24)10-26-18/h1-6,10,16,22,24H,8-9,20H2,(H,23,25)/t16-/m1/s1.
What are the key properties of N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide?
N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide has a molecular weight of 367.43 g/mol, XLogP of 1.93, 6 rotatable bonds, 4 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for N-[(1R)-2-amino-1-[4-(hydroxymethyl)-1,3-thiazol-2-yl]ethyl]-5-(4-cyanophenyl)-1H-pyrrole-2-carboxamide is sourced from PubChem (CID 168509938), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).