About methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate
methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate (PubChem CID 169058673) has the molecular formula C23H22F6N6O2
and a molecular weight of 528.46 g/mol. Its IUPAC name is methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate.
Molecular Properties
| Compound Name | methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate |
| PubChem CID | 169058673 |
| Molecular Formula | C23H22F6N6O2 |
| Molecular Weight | 528.46 g/mol |
| Exact Mass | 528.17 |
| IUPAC Name | methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate |
| SMILES | COC(=O)Nc1ccc2c(-c3nc(N[C@H]4CCC5(CC5)NC4)ncc3C(F)(F)F)c[nH]c2c1C(F)(F)F |
| InChI | InChI=1S/C23H22F6N6O2/c1-37-20(36)34-15-3-2-12-13(9-30-18(12)16(15)23(27,28)29)17-14(22(24,25)26)10-31-19(35-17)33-11-4-5-21(6-7-21)32-8-11/h2-3,9-11,30,32H,4-8H2,1H3,(H,34,36)(H,31,33,35)/t11-/m0/s1 |
| InChIKey | PDHYEDWAMAUZFQ-NSHDSACASA-N |
| XLogP | 5.54 |
| TPSA | 103.96 Ų |
| H-Bond Donors | 4 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 37 |
| Complexity | — |
Lipinski Rule of Five
2 violations
| Rule | Value |
| MW ≤ 500 | 528.46 |
| LogP ≤ 5 | 5.54 |
| H-Bond Donors ≤ 5 | 4 |
| H-Bond Acceptors ≤ 10 | 6 |
Analyze methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate with MolForge
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Frequently Asked Questions
What is the IUPAC name of methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate?
The IUPAC name of methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate (CID 169058673) is methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate.
What is the SMILES notation for methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate?
The canonical SMILES for methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate is COC(=O)Nc1ccc2c(-c3nc(N[C@H]4CCC5(CC5)NC4)ncc3C(F)(F)F)c[nH]c2c1C(F)(F)F.
What is the InChIKey of methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate?
The InChIKey is PDHYEDWAMAUZFQ-NSHDSACASA-N. The full InChI is InChI=1S/C23H22F6N6O2/c1-37-20(36)34-15-3-2-12-13(9-30-18(12)16(15)23(27,28)29)17-14(22(24,25)26)10-31-19(35-17)33-11-4-5-21(6-7-21)32-8-11/h2-3,9-11,30,32H,4-8H2,1H3,(H,34,36)(H,31,33,35)/t11-/m0/s1.
What are the key properties of methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate?
methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate has a molecular weight of 528.46 g/mol, XLogP of 5.54, 4 rotatable bonds, 4 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for methyl N-[3-[2-[[(6S)-4-azaspiro[2.5]octan-6-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-7-(trifluoromethyl)-1H-indol-6-yl]carbamate is sourced from PubChem (CID 169058673), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).