(2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide

C17H15ClF3N5O2 — CID 169245334

IUPAC(2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide
SMILESC[C@@H](C(=O)Nc1cc(C2CC2)[nH]n1)c1cn2cc(Cl)cc(OC(F)(F)F)c2n1
InChIInChI=1S/C17H15ClF3N5O2/c1-8(16(27)23-14-5-11(24-25-14)9-2-3-9)12-7-26-6-10(18)4-13(15(26)22-12)28-17(19,20)21/h4-9H,2-3H2,1H3,(H2,23,24,25,27)/t8-/m1/s1
InChIKeyOJMIJUXUHQLTII-MRVPVSSYSA-N
MW413.79 g/mol
LogP4.23
Rot. Bonds5

About (2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide

(2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide (PubChem CID 169245334) has the molecular formula C17H15ClF3N5O2 and a molecular weight of 413.79 g/mol. Its IUPAC name is (2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide.

Molecular Properties

Compound Name(2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide
PubChem CID169245334
Molecular FormulaC17H15ClF3N5O2
Molecular Weight413.79 g/mol
Exact Mass413.09
IUPAC Name(2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide
SMILESC[C@@H](C(=O)Nc1cc(C2CC2)[nH]n1)c1cn2cc(Cl)cc(OC(F)(F)F)c2n1
InChIInChI=1S/C17H15ClF3N5O2/c1-8(16(27)23-14-5-11(24-25-14)9-2-3-9)12-7-26-6-10(18)4-13(15(26)22-12)28-17(19,20)21/h4-9H,2-3H2,1H3,(H2,23,24,25,27)/t8-/m1/s1
InChIKeyOJMIJUXUHQLTII-MRVPVSSYSA-N
XLogP4.23
TPSA84.31 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds5
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500413.79
LogP ≤ 54.23
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

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Related Compounds

N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(6-fluoro-7-methylimidazo[1,2-a]pyridin-2-yl)propanamide
CID 169245199
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CID 162513055
(Z)-4-amino-3-[(3-chlorophenyl)iminomethyl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-methylbut-3-enamide
CID 176713770
(2R)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(3-methyl-2-oxoimidazolidin-1-yl)phenyl]propanamide
CID 5330964
N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[6-(1-prop-2-enoyl-3,6-dihydro-2H-pyridin-4-yl)pyridazin-3-yl]propanamide
CID 139558759
N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxopiperidin-1-yl)phenyl]propanamide
CID 5330950
N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[[2-(3,4-difluorophenyl)acetyl]amino]propanamide
CID 90932431
N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-ethyl-5-methyl-4-oxoheptanamide
CID 169245129
(2R)-N-(5-cyclopentyl-1H-pyrazol-3-yl)-2-pyridin-3-ylpropanamide
CID 164630164
(2S)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-[(prop-2-enoylamino)methyl]phenyl]propanamide
CID 155168097
N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(3-pyrazin-2-ylphenyl)propanamide
CID 160563832
2-[4-(3-chloro-4-fluorophenyl)phenyl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)acetamide
CID 22176703

Frequently Asked Questions

What is the IUPAC name of (2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide?
The IUPAC name of (2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide (CID 169245334) is (2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide.
What is the SMILES notation for (2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide?
The canonical SMILES for (2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide is C[C@@H](C(=O)Nc1cc(C2CC2)[nH]n1)c1cn2cc(Cl)cc(OC(F)(F)F)c2n1.
What is the InChIKey of (2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide?
The InChIKey is OJMIJUXUHQLTII-MRVPVSSYSA-N. The full InChI is InChI=1S/C17H15ClF3N5O2/c1-8(16(27)23-14-5-11(24-25-14)9-2-3-9)12-7-26-6-10(18)4-13(15(26)22-12)28-17(19,20)21/h4-9H,2-3H2,1H3,(H2,23,24,25,27)/t8-/m1/s1.
What are the key properties of (2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide?
(2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide has a molecular weight of 413.79 g/mol, XLogP of 4.23, 5 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for (2R)-2-[6-chloro-8-(trifluoromethoxy)imidazo[1,2-a]pyridin-2-yl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide is sourced from PubChem (CID 169245334), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).