About 5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one
5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one (PubChem CID 169491277) has the molecular formula C22H14F3N5O
and a molecular weight of 421.38 g/mol. Its IUPAC name is 5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one.
Molecular Properties
| Compound Name | 5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one |
| PubChem CID | 169491277 |
| Molecular Formula | C22H14F3N5O |
| Molecular Weight | 421.38 g/mol |
| Exact Mass | 421.12 |
| IUPAC Name | 5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one |
| SMILES | [H]/N=C1/C(c2cccc3[nH]ncc23)=CC(c2cccc(C(F)(F)F)c2)=C2N=CNC(=O)C21 |
| InChI | InChI=1S/C22H14F3N5O/c23-22(24,25)12-4-1-3-11(7-12)14-8-15(13-5-2-6-17-16(13)9-29-30-17)19(26)18-20(14)27-10-28-21(18)31/h1-10,18,26H,(H,29,30)(H,27,28,31)/b26-19- |
| InChIKey | FNEBUZZCWPRDNG-XHPQRKPJSA-N |
| XLogP | 4.18 |
| TPSA | 93.99 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Heavy Atoms | 31 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 421.38 |
| LogP ≤ 5 | 4.18 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'imine_1', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one?
The IUPAC name of 5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one (CID 169491277) is 5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one.
What is the SMILES notation for 5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one?
The canonical SMILES for 5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one is [H]/N=C1/C(c2cccc3[nH]ncc23)=CC(c2cccc(C(F)(F)F)c2)=C2N=CNC(=O)C21.
What is the InChIKey of 5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one?
The InChIKey is FNEBUZZCWPRDNG-XHPQRKPJSA-N. The full InChI is InChI=1S/C22H14F3N5O/c23-22(24,25)12-4-1-3-11(7-12)14-8-15(13-5-2-6-17-16(13)9-29-30-17)19(26)18-20(14)27-10-28-21(18)31/h1-10,18,26H,(H,29,30)(H,27,28,31)/b26-19-.
What are the key properties of 5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one?
5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one has a molecular weight of 421.38 g/mol, XLogP of 4.18, 2 rotatable bonds, 3 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 5-imino-6-(1H-indazol-4-yl)-8-[3-(trifluoromethyl)phenyl]-3,4a-dihydroquinazolin-4-one is sourced from PubChem (CID 169491277), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).