About 4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide
4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide (PubChem CID 171433736) has the molecular formula C25H26ClFN4O
and a molecular weight of 452.96 g/mol. Its IUPAC name is 4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide.
Molecular Properties
| Compound Name | 4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide |
| PubChem CID | 171433736 |
| Molecular Formula | C25H26ClFN4O |
| Molecular Weight | 452.96 g/mol |
| Exact Mass | 452.18 |
| IUPAC Name | 4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide |
| SMILES | Cc1ccc(-c2cc(CN3CCC(F)CC3)cc(NC(=O)c3cc(Cl)c(C)cn3)c2)cn1 |
| InChI | InChI=1S/C25H26ClFN4O/c1-16-13-29-24(12-23(16)26)25(32)30-22-10-18(15-31-7-5-21(27)6-8-31)9-20(11-22)19-4-3-17(2)28-14-19/h3-4,9-14,21H,5-8,15H2,1-2H3,(H,30,32) |
| InChIKey | OWMCEILDMCCISU-UHFFFAOYSA-N |
| XLogP | 5.60 |
| TPSA | 58.12 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 32 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 452.96 |
| LogP ≤ 5 | 5.60 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
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Frequently Asked Questions
What is the IUPAC name of 4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide?
The IUPAC name of 4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide (CID 171433736) is 4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide.
What is the SMILES notation for 4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide?
The canonical SMILES for 4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide is Cc1ccc(-c2cc(CN3CCC(F)CC3)cc(NC(=O)c3cc(Cl)c(C)cn3)c2)cn1.
What is the InChIKey of 4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide?
The InChIKey is OWMCEILDMCCISU-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H26ClFN4O/c1-16-13-29-24(12-23(16)26)25(32)30-22-10-18(15-31-7-5-21(27)6-8-31)9-20(11-22)19-4-3-17(2)28-14-19/h3-4,9-14,21H,5-8,15H2,1-2H3,(H,30,32).
What are the key properties of 4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide?
4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide has a molecular weight of 452.96 g/mol, XLogP of 5.60, 5 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 4-chloro-N-[3-[(4-fluoropiperidin-1-yl)methyl]-5-(6-methyl-3-pyridinyl)phenyl]-5-methylpyridine-2-carboxamide is sourced from PubChem (CID 171433736), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).