About 3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one
3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one (PubChem CID 171648334) has the molecular formula C22H25F6N7O2
and a molecular weight of 533.48 g/mol. Its IUPAC name is 3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one.
Molecular Properties
| Compound Name | 3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one |
| PubChem CID | 171648334 |
| Molecular Formula | C22H25F6N7O2 |
| Molecular Weight | 533.48 g/mol |
| Exact Mass | 533.20 |
| IUPAC Name | 3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one |
| SMILES | O=C(CCN1CCCC(c2cc(C(F)(F)F)c(=O)[nH]n2)C1)N1CCN(c2ncc(C(F)(F)F)cn2)CC1 |
| InChI | InChI=1S/C22H25F6N7O2/c23-21(24,25)15-11-29-20(30-12-15)35-8-6-34(7-9-35)18(36)3-5-33-4-1-2-14(13-33)17-10-16(22(26,27)28)19(37)32-31-17/h10-12,14H,1-9,13H2,(H,32,37) |
| InChIKey | JOTIDRAIQDKUSQ-UHFFFAOYSA-N |
| XLogP | 2.52 |
| TPSA | 98.32 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 37 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 533.48 |
| LogP ≤ 5 | 2.52 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 7 |
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Frequently Asked Questions
What is the IUPAC name of 3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one?
The IUPAC name of 3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one (CID 171648334) is 3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one.
What is the SMILES notation for 3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one?
The canonical SMILES for 3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one is O=C(CCN1CCCC(c2cc(C(F)(F)F)c(=O)[nH]n2)C1)N1CCN(c2ncc(C(F)(F)F)cn2)CC1.
What is the InChIKey of 3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one?
The InChIKey is JOTIDRAIQDKUSQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H25F6N7O2/c23-21(24,25)15-11-29-20(30-12-15)35-8-6-34(7-9-35)18(36)3-5-33-4-1-2-14(13-33)17-10-16(22(26,27)28)19(37)32-31-17/h10-12,14H,1-9,13H2,(H,32,37).
What are the key properties of 3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one?
3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one has a molecular weight of 533.48 g/mol, XLogP of 2.52, 5 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[1-[3-oxo-3-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]propyl]piperidin-3-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one is sourced from PubChem (CID 171648334), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).