About 6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile
6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile (PubChem CID 172625934) has the molecular formula C18H17F2N5O
and a molecular weight of 357.36 g/mol. Its IUPAC name is 6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile.
Molecular Properties
| Compound Name | 6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile |
| PubChem CID | 172625934 |
| Molecular Formula | C18H17F2N5O |
| Molecular Weight | 357.36 g/mol |
| Exact Mass | 357.14 |
| IUPAC Name | 6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile |
| SMILES | COc1ccc(C)c(-n2c(N)c(C#N)c3c(C(F)F)nc(C)nc32)c1C |
| InChI | InChI=1S/C18H17F2N5O/c1-8-5-6-12(26-4)9(2)15(8)25-17(22)11(7-21)13-14(16(19)20)23-10(3)24-18(13)25/h5-6,16H,22H2,1-4H3 |
| InChIKey | VFSXTLFDZDQXLY-UHFFFAOYSA-N |
| XLogP | 3.75 |
| TPSA | 89.75 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 26 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 357.36 |
| LogP ≤ 5 | 3.75 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of 6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile?
The IUPAC name of 6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile (CID 172625934) is 6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile.
What is the SMILES notation for 6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile?
The canonical SMILES for 6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile is COc1ccc(C)c(-n2c(N)c(C#N)c3c(C(F)F)nc(C)nc32)c1C.
What is the InChIKey of 6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile?
The InChIKey is VFSXTLFDZDQXLY-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H17F2N5O/c1-8-5-6-12(26-4)9(2)15(8)25-17(22)11(7-21)13-14(16(19)20)23-10(3)24-18(13)25/h5-6,16H,22H2,1-4H3.
What are the key properties of 6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile?
6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile has a molecular weight of 357.36 g/mol, XLogP of 3.75, 3 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 6-amino-4-(difluoromethyl)-7-(3-methoxy-2,6-dimethylphenyl)-2-methylpyrrolo[2,3-d]pyrimidine-5-carbonitrile is sourced from PubChem (CID 172625934), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).