2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide

C107H84F20N32O11 — CID 173170753

IUPAC2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide
SMILESCCC(=O)Nc1cnc(-n2c(C(F)(F)F)nc3cc(OC)ccc32)cn1.CCC(C)(C(N)=O)c1cnc(-n2c(C(F)(F)F)nc3cc(OC)ccc32)cn1.COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(N)cn1.COc1ccc2nc(C(F)(F)F)n(-c3cnc(NC(=O)c4c(F)cccc4F)cn3)c2c1.COc1ccc2nc(C(F)(F)F)n(-c3cnc(NC(=O)c4cccnc4C)cn3)c2c1.COc1ccc2nc(C(F)(F)F)n(-c3cnc(NC(=O)c4ccncc4C)cn3)c2c1
InChIInChI=1S/C20H12F5N5O2.2C20H15F3N6O2.C18H18F3N5O2.C16H14F3N5O2.C13H10F3N5O/c1-32-10-5-6-13-14(7-10)30(19(28-13)20(23,24)25)16-9-26-15(8-27-16)29-18(31)17-11(21)3-2-4-12(17)22;1-11-8-24-6-5-13(11)18(30)28-16-9-26-17(10-25-16)29-15-7-12(31-2)3-4-14(15)27-19(29)20(21,22)23;1-11-13(4-3-7-24-11)18(30)28-16-9-26-17(10-25-16)29-15-8-12(31-2)5-6-14(15)27-19(29)20(21,22)23;1-4-17(2,15(22)27)13-8-24-14(9-23-13)26-12-6-5-10(28-3)7-11(12)25-16(26)18(19,20)21;1-3-14(25)23-12-7-21-13(8-20-12)24-11-5-4-9(26-2)6-10(11)22-15(24)16(17,18)19;1-22-7-2-3-9-8(4-7)20-12(13(14,15)16)21(9)11-6-18-10(17)5-19-11/h2-9H,1H3,(H,26,29,31);2*3-10H,1-2H3,(H,25,28,30);5-9H,4H2,1-3H3,(H2,22,27);4-8H,3H2,1-2H3,(H,20,23,25);2-6H,1H3,(H2,17,18)
InChIKeyLRRFTGYVHQQHFS-UHFFFAOYSA-N
MW2374.02 g/mol
LogP20.58
Rot. Bonds23

About 2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide

2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide (PubChem CID 173170753) has the molecular formula C107H84F20N32O11 and a molecular weight of 2374.02 g/mol. Its IUPAC name is 2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide.

Molecular Properties

Compound Name2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide
PubChem CID173170753
Molecular FormulaC107H84F20N32O11
Molecular Weight2374.02 g/mol
Exact Mass2372.67
IUPAC Name2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide
SMILESCCC(=O)Nc1cnc(-n2c(C(F)(F)F)nc3cc(OC)ccc32)cn1.CCC(C)(C(N)=O)c1cnc(-n2c(C(F)(F)F)nc3cc(OC)ccc32)cn1.COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(N)cn1.COc1ccc2nc(C(F)(F)F)n(-c3cnc(NC(=O)c4c(F)cccc4F)cn3)c2c1.COc1ccc2nc(C(F)(F)F)n(-c3cnc(NC(=O)c4cccnc4C)cn3)c2c1.COc1ccc2nc(C(F)(F)F)n(-c3cnc(NC(=O)c4ccncc4C)cn3)c2c1
InChIInChI=1S/C20H12F5N5O2.2C20H15F3N6O2.C18H18F3N5O2.C16H14F3N5O2.C13H10F3N5O/c1-32-10-5-6-13-14(7-10)30(19(28-13)20(23,24)25)16-9-26-15(8-27-16)29-18(31)17-11(21)3-2-4-12(17)22;1-11-8-24-6-5-13(11)18(30)28-16-9-26-17(10-25-16)29-15-7-12(31-2)3-4-14(15)27-19(29)20(21,22)23;1-11-13(4-3-7-24-11)18(30)28-16-9-26-17(10-25-16)29-15-8-12(31-2)5-6-14(15)27-19(29)20(21,22)23;1-4-17(2,15(22)27)13-8-24-14(9-23-13)26-12-6-5-10(28-3)7-11(12)25-16(26)18(19,20)21;1-3-14(25)23-12-7-21-13(8-20-12)24-11-5-4-9(26-2)6-10(11)22-15(24)16(17,18)19;1-22-7-2-3-9-8(4-7)20-12(13(14,15)16)21(9)11-6-18-10(17)5-19-11/h2-9H,1H3,(H,26,29,31);2*3-10H,1-2H3,(H,25,28,30);5-9H,4H2,1-3H3,(H2,22,27);4-8H,3H2,1-2H3,(H,20,23,25);2-6H,1H3,(H2,17,18)
InChIKeyLRRFTGYVHQQHFS-UHFFFAOYSA-N
XLogP20.58
TPSA528.27 Ų
H-Bond Donors6
H-Bond Acceptors38
Rotatable Bonds23
Heavy Atoms170
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5002374.02
LogP ≤ 520.58
H-Bond Donors ≤ 56
H-Bond Acceptors ≤ 1038

Analyze 2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of 2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide?
The IUPAC name of 2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide (CID 173170753) is 2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide.
What is the SMILES notation for 2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide?
The canonical SMILES for 2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide is CCC(=O)Nc1cnc(-n2c(C(F)(F)F)nc3cc(OC)ccc32)cn1.CCC(C)(C(N)=O)c1cnc(-n2c(C(F)(F)F)nc3cc(OC)ccc32)cn1.COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(N)cn1.COc1ccc2nc(C(F)(F)F)n(-c3cnc(NC(=O)c4c(F)cccc4F)cn3)c2c1.COc1ccc2nc(C(F)(F)F)n(-c3cnc(NC(=O)c4cccnc4C)cn3)c2c1.COc1ccc2nc(C(F)(F)F)n(-c3cnc(NC(=O)c4ccncc4C)cn3)c2c1.
What is the InChIKey of 2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide?
The InChIKey is LRRFTGYVHQQHFS-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H12F5N5O2.2C20H15F3N6O2.C18H18F3N5O2.C16H14F3N5O2.C13H10F3N5O/c1-32-10-5-6-13-14(7-10)30(19(28-13)20(23,24)25)16-9-26-15(8-27-16)29-18(31)17-11(21)3-2-4-12(17)22;1-11-8-24-6-5-13(11)18(30)28-16-9-26-17(10-25-16)29-15-7-12(31-2)3-4-14(15)27-19(29)20(21,22)23;1-11-13(4-3-7-24-11)18(30)28-16-9-26-17(10-25-16)29-15-8-12(31-2)5-6-14(15)27-19(29)20(21,22)23;1-4-17(2,15(22)27)13-8-24-14(9-23-13)26-12-6-5-10(28-3)7-11(12)25-16(26)18(19,20)21;1-3-14(25)23-12-7-21-13(8-20-12)24-11-5-4-9(26-2)6-10(11)22-15(24)16(17,18)19;1-22-7-2-3-9-8(4-7)20-12(13(14,15)16)21(9)11-6-18-10(17)5-19-11/h2-9H,1H3,(H,26,29,31);2*3-10H,1-2H3,(H,25,28,30);5-9H,4H2,1-3H3,(H2,22,27);4-8H,3H2,1-2H3,(H,20,23,25);2-6H,1H3,(H2,17,18).
What are the key properties of 2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide?
2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide has a molecular weight of 2374.02 g/mol, XLogP of 20.58, 23 rotatable bonds, 6 hydrogen bond donors, and 38 hydrogen bond acceptors.
Where does this data come from?
All data for 2,6-difluoro-N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]benzamide;5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-amine;2-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylbutanamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-2-methylpyridine-3-carboxamide;N-[5-[6-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]-3-methylpyridine-4-carboxamide;N-[5-[5-methoxy-2-(trifluoromethyl)benzimidazol-1-yl]pyrazin-2-yl]propanamide is sourced from PubChem (CID 173170753), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).