About 4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid
4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid (PubChem CID 174146239) has the molecular formula C20H15Cl2N3O4S
and a molecular weight of 464.33 g/mol. Its IUPAC name is 4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid.
Molecular Properties
| Compound Name | 4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid |
| PubChem CID | 174146239 |
| Molecular Formula | C20H15Cl2N3O4S |
| Molecular Weight | 464.33 g/mol |
| Exact Mass | 463.02 |
| IUPAC Name | 4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid |
| SMILES | CC1=C(C(=O)O)C(c2ccc(OC(=O)C=Cc3ccnc(Cl)c3)c(Cl)c2)NC(=S)N1 |
| InChI | InChI=1S/C20H15Cl2N3O4S/c1-10-17(19(27)28)18(25-20(30)24-10)12-3-4-14(13(21)9-12)29-16(26)5-2-11-6-7-23-15(22)8-11/h2-9,18H,1H3,(H,27,28)(H2,24,25,30) |
| InChIKey | CKUHWAOPXQUZJN-UHFFFAOYSA-N |
| XLogP | 3.88 |
| TPSA | 100.55 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 30 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 464.33 |
| LogP ≤ 5 | 3.88 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': '2-halo_pyridine', 'substructure': 'N/A'}, {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}, {'alert_name': 'phenol_ester', 'substructure': 'N/A'}, {'alert_name': 'Thiocarbonyl_group', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid?
The IUPAC name of 4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid (CID 174146239) is 4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid.
What is the SMILES notation for 4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid?
The canonical SMILES for 4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid is CC1=C(C(=O)O)C(c2ccc(OC(=O)C=Cc3ccnc(Cl)c3)c(Cl)c2)NC(=S)N1.
What is the InChIKey of 4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid?
The InChIKey is CKUHWAOPXQUZJN-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H15Cl2N3O4S/c1-10-17(19(27)28)18(25-20(30)24-10)12-3-4-14(13(21)9-12)29-16(26)5-2-11-6-7-23-15(22)8-11/h2-9,18H,1H3,(H,27,28)(H2,24,25,30).
What are the key properties of 4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid?
4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid has a molecular weight of 464.33 g/mol, XLogP of 3.88, 5 rotatable bonds, 3 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[3-chloro-4-[3-(2-chloro-4-pyridinyl)prop-2-enoyloxy]phenyl]-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylic acid is sourced from PubChem (CID 174146239), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).