N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

C91H86F6N24O8 — CID 174154910

IUPACN-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
SMILESN#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(OC2(C(F)(F)F)CCNCC2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@@H]2CCN[C@H](C(F)(F)F)C2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@H]2CCN(C3CC3)C2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@H]2CCNC2)cn1
InChIInChI=1S/C24H24N6O2.2C23H21F3N6O2.C21H20N6O2/c25-12-17-10-21(22(13-26-17)32-20-6-7-29(14-20)18-3-4-18)16-5-8-30-19(9-16)11-23(28-30)27-24(31)15-1-2-15;24-23(25,26)22(4-6-28-7-5-22)34-19-13-29-16(12-27)10-18(19)15-3-8-32-17(9-15)11-20(31-32)30-21(33)14-1-2-14;24-23(25,26)20-10-17(3-5-28-20)34-19-12-29-15(11-27)8-18(19)14-4-6-32-16(7-14)9-21(31-32)30-22(33)13-1-2-13;22-10-15-8-18(19(12-24-15)29-17-3-5-23-11-17)14-4-6-27-16(7-14)9-20(26-27)25-21(28)13-1-2-13/h5,8-11,13,15,18,20H,1-4,6-7,14H2,(H,27,28,31);3,8-11,13-14,28H,1-2,4-7H2,(H,30,31,33);4,6-9,12-13,17,20,28H,1-3,5,10H2,(H,30,31,33);4,6-9,12-13,17,23H,1-3,5,11H2,(H,25,26,28)/t20-;;17-,20+;17-/m0.10/s1
InChIKeySEZXRHSRYZDHDX-ZSZYNMHRSA-N
MW1757.84 g/mol
LogP12.95
Rot. Bonds21

About N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide (PubChem CID 174154910) has the molecular formula C91H86F6N24O8 and a molecular weight of 1757.84 g/mol. Its IUPAC name is N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide.

Molecular Properties

Compound NameN-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
PubChem CID174154910
Molecular FormulaC91H86F6N24O8
Molecular Weight1757.84 g/mol
Exact Mass1756.70
IUPAC NameN-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
SMILESN#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(OC2(C(F)(F)F)CCNCC2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@@H]2CCN[C@H](C(F)(F)F)C2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@H]2CCN(C3CC3)C2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@H]2CCNC2)cn1
InChIInChI=1S/C24H24N6O2.2C23H21F3N6O2.C21H20N6O2/c25-12-17-10-21(22(13-26-17)32-20-6-7-29(14-20)18-3-4-18)16-5-8-30-19(9-16)11-23(28-30)27-24(31)15-1-2-15;24-23(25,26)22(4-6-28-7-5-22)34-19-13-29-16(12-27)10-18(19)15-3-8-32-17(9-15)11-20(31-32)30-21(33)14-1-2-14;24-23(25,26)20-10-17(3-5-28-20)34-19-12-29-15(11-27)8-18(19)14-4-6-32-16(7-14)9-21(31-32)30-22(33)13-1-2-13;22-10-15-8-18(19(12-24-15)29-17-3-5-23-11-17)14-4-6-27-16(7-14)9-20(26-27)25-21(28)13-1-2-13/h5,8-11,13,15,18,20H,1-4,6-7,14H2,(H,27,28,31);3,8-11,13-14,28H,1-2,4-7H2,(H,30,31,33);4,6-9,12-13,17,20,28H,1-3,5,10H2,(H,30,31,33);4,6-9,12-13,17,23H,1-3,5,11H2,(H,25,26,28)/t20-;;17-,20+;17-/m0.10/s1
InChIKeySEZXRHSRYZDHDX-ZSZYNMHRSA-N
XLogP12.95
TPSA408.57 Ų
H-Bond Donors7
H-Bond Acceptors28
Rotatable Bonds21
Heavy Atoms129
Complexity—

Lipinski Rule of Five

4 violations

RuleValue
MW ≤ 5001757.84
LogP ≤ 512.95
H-Bond Donors ≤ 57
H-Bond Acceptors ≤ 1028

Analyze N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide?
The IUPAC name of N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide (CID 174154910) is N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide.
What is the SMILES notation for N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide?
The canonical SMILES for N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide is N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(OC2(C(F)(F)F)CCNCC2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@@H]2CCN[C@H](C(F)(F)F)C2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@H]2CCN(C3CC3)C2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@H]2CCNC2)cn1.
What is the InChIKey of N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide?
The InChIKey is SEZXRHSRYZDHDX-ZSZYNMHRSA-N. The full InChI is InChI=1S/C24H24N6O2.2C23H21F3N6O2.C21H20N6O2/c25-12-17-10-21(22(13-26-17)32-20-6-7-29(14-20)18-3-4-18)16-5-8-30-19(9-16)11-23(28-30)27-24(31)15-1-2-15;24-23(25,26)22(4-6-28-7-5-22)34-19-13-29-16(12-27)10-18(19)15-3-8-32-17(9-15)11-20(31-32)30-21(33)14-1-2-14;24-23(25,26)20-10-17(3-5-28-20)34-19-12-29-15(11-27)8-18(19)14-4-6-32-16(7-14)9-21(31-32)30-22(33)13-1-2-13;22-10-15-8-18(19(12-24-15)29-17-3-5-23-11-17)14-4-6-27-16(7-14)9-20(26-27)25-21(28)13-1-2-13/h5,8-11,13,15,18,20H,1-4,6-7,14H2,(H,27,28,31);3,8-11,13-14,28H,1-2,4-7H2,(H,30,31,33);4,6-9,12-13,17,20,28H,1-3,5,10H2,(H,30,31,33);4,6-9,12-13,17,23H,1-3,5,11H2,(H,25,26,28)/t20-;;17-,20+;17-/m0.10/s1.
What are the key properties of N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide?
N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide has a molecular weight of 1757.84 g/mol, XLogP of 12.95, 21 rotatable bonds, 7 hydrogen bond donors, and 28 hydrogen bond acceptors.
Where does this data come from?
All data for N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[4-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide is sourced from PubChem (CID 174154910), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).