N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

C68H65F3N18O6 — CID 174155023

IUPACN-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
SMILESN#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@@H]2CCN[C@H](C(F)(F)F)C2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@H]2CCN(C3CC3)C2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@H]2CCNC2)cn1
InChIInChI=1S/C24H24N6O2.C23H21F3N6O2.C21H20N6O2/c25-12-17-10-21(22(13-26-17)32-20-6-7-29(14-20)18-3-4-18)16-5-8-30-19(9-16)11-23(28-30)27-24(31)15-1-2-15;24-23(25,26)20-10-17(3-5-28-20)34-19-12-29-15(11-27)8-18(19)14-4-6-32-16(7-14)9-21(31-32)30-22(33)13-1-2-13;22-10-15-8-18(19(12-24-15)29-17-3-5-23-11-17)14-4-6-27-16(7-14)9-20(26-27)25-21(28)13-1-2-13/h5,8-11,13,15,18,20H,1-4,6-7,14H2,(H,27,28,31);4,6-9,12-13,17,20,28H,1-3,5,10H2,(H,30,31,33);4,6-9,12-13,17,23H,1-3,5,11H2,(H,25,26,28)/t20-;17-,20+;17-/m010/s1
InChIKeyLOWDXNRBNFPURV-ZKSSIASLSA-N
MW1287.38 g/mol
LogP9.27
Rot. Bonds16

About N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide

N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide (PubChem CID 174155023) has the molecular formula C68H65F3N18O6 and a molecular weight of 1287.38 g/mol. Its IUPAC name is N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide.

Molecular Properties

Compound NameN-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
PubChem CID174155023
Molecular FormulaC68H65F3N18O6
Molecular Weight1287.38 g/mol
Exact Mass1286.53
IUPAC NameN-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
SMILESN#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@@H]2CCN[C@H](C(F)(F)F)C2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@H]2CCN(C3CC3)C2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@H]2CCNC2)cn1
InChIInChI=1S/C24H24N6O2.C23H21F3N6O2.C21H20N6O2/c25-12-17-10-21(22(13-26-17)32-20-6-7-29(14-20)18-3-4-18)16-5-8-30-19(9-16)11-23(28-30)27-24(31)15-1-2-15;24-23(25,26)20-10-17(3-5-28-20)34-19-12-29-15(11-27)8-18(19)14-4-6-32-16(7-14)9-21(31-32)30-22(33)13-1-2-13;22-10-15-8-18(19(12-24-15)29-17-3-5-23-11-17)14-4-6-27-16(7-14)9-20(26-27)25-21(28)13-1-2-13/h5,8-11,13,15,18,20H,1-4,6-7,14H2,(H,27,28,31);4,6-9,12-13,17,20,28H,1-3,5,10H2,(H,30,31,33);4,6-9,12-13,17,23H,1-3,5,11H2,(H,25,26,28)/t20-;17-,20+;17-/m010/s1
InChIKeyLOWDXNRBNFPURV-ZKSSIASLSA-N
XLogP9.27
TPSA304.23 Ų
H-Bond Donors5
H-Bond Acceptors21
Rotatable Bonds16
Heavy Atoms95
Complexity—

Lipinski Rule of Five

3 violations

RuleValue
MW ≤ 5001287.38
LogP ≤ 59.27
H-Bond Donors ≤ 55
H-Bond Acceptors ≤ 1021

Analyze N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide with MolForge

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Frequently Asked Questions

What is the IUPAC name of N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide?
The IUPAC name of N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide (CID 174155023) is N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide.
What is the SMILES notation for N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide?
The canonical SMILES for N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide is N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@@H]2CCN[C@H](C(F)(F)F)C2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@H]2CCN(C3CC3)C2)cn1.N#Cc1cc(-c2ccn3nc(NC(=O)C4CC4)cc3c2)c(O[C@H]2CCNC2)cn1.
What is the InChIKey of N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide?
The InChIKey is LOWDXNRBNFPURV-ZKSSIASLSA-N. The full InChI is InChI=1S/C24H24N6O2.C23H21F3N6O2.C21H20N6O2/c25-12-17-10-21(22(13-26-17)32-20-6-7-29(14-20)18-3-4-18)16-5-8-30-19(9-16)11-23(28-30)27-24(31)15-1-2-15;24-23(25,26)20-10-17(3-5-28-20)34-19-12-29-15(11-27)8-18(19)14-4-6-32-16(7-14)9-21(31-32)30-22(33)13-1-2-13;22-10-15-8-18(19(12-24-15)29-17-3-5-23-11-17)14-4-6-27-16(7-14)9-20(26-27)25-21(28)13-1-2-13/h5,8-11,13,15,18,20H,1-4,6-7,14H2,(H,27,28,31);4,6-9,12-13,17,20,28H,1-3,5,10H2,(H,30,31,33);4,6-9,12-13,17,23H,1-3,5,11H2,(H,25,26,28)/t20-;17-,20+;17-/m010/s1.
What are the key properties of N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide?
N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide has a molecular weight of 1287.38 g/mol, XLogP of 9.27, 16 rotatable bonds, 5 hydrogen bond donors, and 21 hydrogen bond acceptors.
Where does this data come from?
All data for N-[5-[2-cyano-5-[(3S)-1-cyclopropylpyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(3S)-pyrrolidin-3-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide;N-[5-[2-cyano-5-[(2S,4R)-2-(trifluoromethyl)piperidin-4-yl]oxy-4-pyridinyl]pyrazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide is sourced from PubChem (CID 174155023), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).