About N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide
N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide (PubChem CID 175335117) has the molecular formula C22H16N4OS
and a molecular weight of 384.46 g/mol. Its IUPAC name is N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide.
Molecular Properties
| Compound Name | N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide |
| PubChem CID | 175335117 |
| Molecular Formula | C22H16N4OS |
| Molecular Weight | 384.46 g/mol |
| Exact Mass | 384.10 |
| IUPAC Name | N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide |
| SMILES | O=C(Nc1cncc(-c2ccc3n[nH]c(C#Cc4ccsc4)c3c2)c1)C1CC1 |
| InChI | InChI=1S/C22H16N4OS/c27-22(15-2-3-15)24-18-9-17(11-23-12-18)16-4-6-21-19(10-16)20(25-26-21)5-1-14-7-8-28-13-14/h4,6-13,15H,2-3H2,(H,24,27)(H,25,26) |
| InChIKey | RDPNHJVOFUZMSM-UHFFFAOYSA-N |
| XLogP | 4.43 |
| TPSA | 70.67 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 28 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 384.46 |
| LogP ≤ 5 | 4.43 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'triple_bond', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide?
The IUPAC name of N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide (CID 175335117) is N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide.
What is the SMILES notation for N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide?
The canonical SMILES for N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide is O=C(Nc1cncc(-c2ccc3n[nH]c(C#Cc4ccsc4)c3c2)c1)C1CC1.
What is the InChIKey of N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide?
The InChIKey is RDPNHJVOFUZMSM-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H16N4OS/c27-22(15-2-3-15)24-18-9-17(11-23-12-18)16-4-6-21-19(10-16)20(25-26-21)5-1-14-7-8-28-13-14/h4,6-13,15H,2-3H2,(H,24,27)(H,25,26).
What are the key properties of N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide?
N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide has a molecular weight of 384.46 g/mol, XLogP of 4.43, 3 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-[5-[3-(2-thiophen-3-ylethynyl)-2H-indazol-5-yl]-3-pyridinyl]cyclopropanecarboxamide is sourced from PubChem (CID 175335117), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).