N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide

C26H19F2N5O2 — CID 175682407

About N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide

N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide (PubChem CID 175682407) has the molecular formula C26H19F2N5O2 and a molecular weight of 471.47 g/mol. Its IUPAC name is N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide
• PubChem CID: 175682407
• Molecular Formula: C26H19F2N5O2
• Molecular Weight: 471.47 g/mol
• Exact Mass: 471.15
• IUPAC Name: N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide
• SMILES: Cc1ccc(-c2noc([C@H]3C[C@@H]3F)n2)cc1NC(=O)c1cnn2ccc(-c3ccc(F)cc3)cc12
• InChI: InChI=1S/C26H19F2N5O2/c1-14-2-3-17(24-31-26(35-32-24)19-12-21(19)28)10-22(14)30-25(34)20-13-29-33-9-8-16(11-23(20)33)15-4-6-18(27)7-5-15/h2-11,13,19,21H,12H2,1H3,(H,30,34)/t19-,21-/m0/s1
• InChIKey: GXDZYJXIPMJQFX-FPOVZHCZSA-N
• XLogP: 5.58
• TPSA: 85.32 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 6
• Rotatable Bonds: 5
• Heavy Atoms: 35
• Complexity: —

Lipinski Rule of Five

1 violation

Rule	Value
MW ≤ 500	471.47
LogP ≤ 5	5.58
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	6

Frequently Asked Questions

What is the IUPAC name of N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide?

The IUPAC name of N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide (CID 175682407) is N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide.

What is the SMILES notation for N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide?

The canonical SMILES for N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide is Cc1ccc(-c2noc([C@H]3C[C@@H]3F)n2)cc1NC(=O)c1cnn2ccc(-c3ccc(F)cc3)cc12.

What is the InChIKey of N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide?

The InChIKey is GXDZYJXIPMJQFX-FPOVZHCZSA-N. The full InChI is InChI=1S/C26H19F2N5O2/c1-14-2-3-17(24-31-26(35-32-24)19-12-21(19)28)10-22(14)30-25(34)20-13-29-33-9-8-16(11-23(20)33)15-4-6-18(27)7-5-15/h2-11,13,19,21H,12H2,1H3,(H,30,34)/t19-,21-/m0/s1.

What are the key properties of N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide?

N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide has a molecular weight of 471.47 g/mol, XLogP of 5.58, 5 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]-5-(4-fluorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide is sourced from PubChem (CID 175682407), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).