N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide

C27H26N6O2 — CID 175682874

About N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide

N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide (PubChem CID 175682874) has the molecular formula C27H26N6O2 and a molecular weight of 466.55 g/mol. Its IUPAC name is N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide.

Molecular Properties

• Compound Name: N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide
• PubChem CID: 175682874
• Molecular Formula: C27H26N6O2
• Molecular Weight: 466.55 g/mol
• Exact Mass: 466.21
• IUPAC Name: N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide
• SMILES: Cc1ccc(-c2cnc(C3CC3)cn2)cc1NC(=O)c1cnn2ccc(N3CC4(COC4)C3)cc12
• InChI: InChI=1S/C27H26N6O2/c1-17-2-3-19(24-12-28-23(11-29-24)18-4-5-18)8-22(17)31-26(34)21-10-30-33-7-6-20(9-25(21)33)32-13-27(14-32)15-35-16-27/h2-3,6-12,18H,4-5,13-16H2,1H3,(H,31,34)
• InChIKey: NQYZTQICKSFTBJ-UHFFFAOYSA-N
• XLogP: 4.07
• TPSA: 84.65 Ų
• H-Bond Donors: 1
• H-Bond Acceptors: 7
• Rotatable Bonds: 5
• Heavy Atoms: 35
• Complexity: —

Lipinski Rule of Five

Passes Rule of Five

Rule	Value
MW ≤ 500	466.55
LogP ≤ 5	4.07
H-Bond Donors ≤ 5	1
H-Bond Acceptors ≤ 10	7

Frequently Asked Questions

What is the IUPAC name of N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide?

The IUPAC name of N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide (CID 175682874) is N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide.

What is the SMILES notation for N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide?

The canonical SMILES for N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide is Cc1ccc(-c2cnc(C3CC3)cn2)cc1NC(=O)c1cnn2ccc(N3CC4(COC4)C3)cc12.

What is the InChIKey of N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide?

The InChIKey is NQYZTQICKSFTBJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H26N6O2/c1-17-2-3-19(24-12-28-23(11-29-24)18-4-5-18)8-22(17)31-26(34)21-10-30-33-7-6-20(9-25(21)33)32-13-27(14-32)15-35-16-27/h2-3,6-12,18H,4-5,13-16H2,1H3,(H,31,34).

What are the key properties of N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide?

N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide has a molecular weight of 466.55 g/mol, XLogP of 4.07, 5 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.

Where does this data come from?

All data for N-[5-(5-cyclopropylpyrazin-2-yl)-2-methylphenyl]-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyrazolo[1,5-a]pyridine-3-carboxamide is sourced from PubChem (CID 175682874), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).