About 3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid
3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid (PubChem CID 175903144) has the molecular formula C25H32FN7O4
and a molecular weight of 513.57 g/mol. Its IUPAC name is 3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid.
Molecular Properties
| Compound Name | 3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid |
| PubChem CID | 175903144 |
| Molecular Formula | C25H32FN7O4 |
| Molecular Weight | 513.57 g/mol |
| Exact Mass | 513.25 |
| IUPAC Name | 3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid |
| SMILES | CCc1nc(-c2cnn(C)c2CNc2nccc(OCCCF)n2)ncc1OC1CCCC(C(=O)O)C1 |
| InChI | InChI=1S/C25H32FN7O4/c1-3-19-21(37-17-7-4-6-16(12-17)24(34)35)15-28-23(31-19)18-13-30-33(2)20(18)14-29-25-27-10-8-22(32-25)36-11-5-9-26/h8,10,13,15-17H,3-7,9,11-12,14H2,1-2H3,(H,34,35)(H,27,29,32) |
| InChIKey | PCDQLJULPXEOTQ-UHFFFAOYSA-N |
| XLogP | 3.60 |
| TPSA | 137.17 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 10 |
| Rotatable Bonds | 12 |
| Heavy Atoms | 37 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 513.57 |
| LogP ≤ 5 | 3.60 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 10 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid?
The IUPAC name of 3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid (CID 175903144) is 3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid.
What is the SMILES notation for 3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid?
The canonical SMILES for 3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid is CCc1nc(-c2cnn(C)c2CNc2nccc(OCCCF)n2)ncc1OC1CCCC(C(=O)O)C1.
What is the InChIKey of 3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid?
The InChIKey is PCDQLJULPXEOTQ-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H32FN7O4/c1-3-19-21(37-17-7-4-6-16(12-17)24(34)35)15-28-23(31-19)18-13-30-33(2)20(18)14-29-25-27-10-8-22(32-25)36-11-5-9-26/h8,10,13,15-17H,3-7,9,11-12,14H2,1-2H3,(H,34,35)(H,27,29,32).
What are the key properties of 3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid?
3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid has a molecular weight of 513.57 g/mol, XLogP of 3.60, 12 rotatable bonds, 2 hydrogen bond donors, and 10 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[4-ethyl-2-[5-[[[4-(3-fluoropropoxy)pyrimidin-2-yl]amino]methyl]-1-methylpyrazol-4-yl]pyrimidin-5-yl]oxycyclohexane-1-carboxylic acid is sourced from PubChem (CID 175903144), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).