6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane

C44H47ClF2N10O3 — CID 176558772

About 6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane

6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane (PubChem CID 176558772) has the molecular formula C44H47ClF2N10O3 and a molecular weight of 837.38 g/mol. Its IUPAC name is 6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane.

Molecular Properties

• Compound Name: 6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane
• PubChem CID: 176558772
• Molecular Formula: C44H47ClF2N10O3
• Molecular Weight: 837.38 g/mol
• Exact Mass: 836.35
• IUPAC Name: 6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane
• SMILES: C1CC1.CNc1cc(N2CCc3c(-c4ccc(CN5CC6(CCN(Cc7cc(Cl)cc(C8CCC(=O)NC8=O)c7)CC6(F)F)C5)cn4)cccc32)nn2c(C(N)=O)cnc12
• InChI: InChI=1S/C41H41ClF2N10O3.C3H6/c1-46-32-16-35(50-54-34(37(45)56)18-48-38(32)54)53-11-9-30-29(3-2-4-33(30)53)31-7-5-24(17-47-31)19-52-21-40(22-52)10-12-51(23-41(40,43)44)20-25-13-26(15-27(42)14-25)28-6-8-36(55)49-39(28)57;1-2-3-1/h2-5,7,13-18,28,46H,6,8-12,19-23H2,1H3,(H2,45,56)(H,49,55,57);1-3H2
• InChIKey: CMWOTCLPOQEILV-UHFFFAOYSA-N
• XLogP: 6.31
• TPSA: 154.09 Ų
• H-Bond Donors: 3
• H-Bond Acceptors: 11
• Rotatable Bonds: 9
• Heavy Atoms: 60
• Complexity: —

Lipinski Rule of Five

3 violations

Rule	Value
MW ≤ 500	837.38
LogP ≤ 5	6.31
H-Bond Donors ≤ 5	3
H-Bond Acceptors ≤ 10	11

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': 'phthalimide', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of 6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane?

The IUPAC name of 6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane (CID 176558772) is 6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane.

What is the SMILES notation for 6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane?

The canonical SMILES for 6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane is C1CC1.CNc1cc(N2CCc3c(-c4ccc(CN5CC6(CCN(Cc7cc(Cl)cc(C8CCC(=O)NC8=O)c7)CC6(F)F)C5)cn4)cccc32)nn2c(C(N)=O)cnc12.

What is the InChIKey of 6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane?

The InChIKey is CMWOTCLPOQEILV-UHFFFAOYSA-N. The full InChI is InChI=1S/C41H41ClF2N10O3.C3H6/c1-46-32-16-35(50-54-34(37(45)56)18-48-38(32)54)53-11-9-30-29(3-2-4-33(30)53)31-7-5-24(17-47-31)19-52-21-40(22-52)10-12-51(23-41(40,43)44)20-25-13-26(15-27(42)14-25)28-6-8-36(55)49-39(28)57;1-2-3-1/h2-5,7,13-18,28,46H,6,8-12,19-23H2,1H3,(H2,45,56)(H,49,55,57);1-3H2.

What are the key properties of 6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane?

6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane has a molecular weight of 837.38 g/mol, XLogP of 6.31, 9 rotatable bonds, 3 hydrogen bond donors, and 11 hydrogen bond acceptors.

Where does this data come from?

All data for 6-[4-[5-[[7-[[3-chloro-5-(2,6-dioxopiperidin-3-yl)phenyl]methyl]-5,5-difluoro-2,7-diazaspiro[3.5]nonan-2-yl]methyl]-2-pyridinyl]-2,3-dihydroindol-1-yl]-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide;cyclopropane is sourced from PubChem (CID 176558772), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).