7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline

C41H43F2N11O6S — CID 177011926

IUPAC7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline
SMILESCN(CCO)S(=O)(=O)Nc1ccc(F)c(Oc2ccc3ncc(C4CCN(C5CC6(C5)CN(c5cc7c(cc5F)c(N5CCC(=O)NC5=O)nn7C)C6)CC4)nc3c2)c1C#N
InChIInChI=1S/C41H43F2N11O6S/c1-50(13-14-55)61(58,59)49-31-6-4-29(42)38(28(31)20-44)60-26-3-5-32-33(15-26)46-34(21-45-32)24-7-10-52(11-8-24)25-18-41(19-25)22-53(23-41)36-17-35-27(16-30(36)43)39(48-51(35)2)54-12-9-37(56)47-40(54)57/h3-6,15-17,21,24-25,49,55H,7-14,18-19,22-23H2,1-2H3,(H,47,56,57)
InChIKeyYZEZUQWAAPRSLA-UHFFFAOYSA-N
MW855.93 g/mol
LogP4.33
Rot. Bonds11

About 7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline

7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline (PubChem CID 177011926) has the molecular formula C41H43F2N11O6S and a molecular weight of 855.93 g/mol. Its IUPAC name is 7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline.

Molecular Properties

Compound Name7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline
PubChem CID177011926
Molecular FormulaC41H43F2N11O6S
Molecular Weight855.93 g/mol
Exact Mass855.31
IUPAC Name7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline
SMILESCN(CCO)S(=O)(=O)Nc1ccc(F)c(Oc2ccc3ncc(C4CCN(C5CC6(C5)CN(c5cc7c(cc5F)c(N5CCC(=O)NC5=O)nn7C)C6)CC4)nc3c2)c1C#N
InChIInChI=1S/C41H43F2N11O6S/c1-50(13-14-55)61(58,59)49-31-6-4-29(42)38(28(31)20-44)60-26-3-5-32-33(15-26)46-34(21-45-32)24-7-10-52(11-8-24)25-18-41(19-25)22-53(23-41)36-17-35-27(16-30(36)43)39(48-51(35)2)54-12-9-37(56)47-40(54)57/h3-6,15-17,21,24-25,49,55H,7-14,18-19,22-23H2,1-2H3,(H,47,56,57)
InChIKeyYZEZUQWAAPRSLA-UHFFFAOYSA-N
XLogP4.33
TPSA202.15 Ų
H-Bond Donors3
H-Bond Acceptors13
Rotatable Bonds11
Heavy Atoms61
Complexity

Lipinski Rule of Five

2 violations

RuleValue
MW ≤ 500855.93
LogP ≤ 54.33
H-Bond Donors ≤ 53
H-Bond Acceptors ≤ 1013

Analyze 7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline with MolForge

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Frequently Asked Questions

What is the IUPAC name of 7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline?
The IUPAC name of 7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline (CID 177011926) is 7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline.
What is the SMILES notation for 7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline?
The canonical SMILES for 7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline is CN(CCO)S(=O)(=O)Nc1ccc(F)c(Oc2ccc3ncc(C4CCN(C5CC6(C5)CN(c5cc7c(cc5F)c(N5CCC(=O)NC5=O)nn7C)C6)CC4)nc3c2)c1C#N.
What is the InChIKey of 7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline?
The InChIKey is YZEZUQWAAPRSLA-UHFFFAOYSA-N. The full InChI is InChI=1S/C41H43F2N11O6S/c1-50(13-14-55)61(58,59)49-31-6-4-29(42)38(28(31)20-44)60-26-3-5-32-33(15-26)46-34(21-45-32)24-7-10-52(11-8-24)25-18-41(19-25)22-53(23-41)36-17-35-27(16-30(36)43)39(48-51(35)2)54-12-9-37(56)47-40(54)57/h3-6,15-17,21,24-25,49,55H,7-14,18-19,22-23H2,1-2H3,(H,47,56,57).
What are the key properties of 7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline?
7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline has a molecular weight of 855.93 g/mol, XLogP of 4.33, 11 rotatable bonds, 3 hydrogen bond donors, and 13 hydrogen bond acceptors.
Where does this data come from?
All data for 7-[2-cyano-6-fluoro-3-[[2-hydroxyethyl(methyl)sulfamoyl]amino]phenoxy]-2-[1-[2-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-2-azaspiro[3.3]heptan-6-yl]piperidin-4-yl]quinoxaline is sourced from PubChem (CID 177011926), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).