About 4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one
4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one (PubChem CID 177204421) has the molecular formula C22H34F3N7O2
and a molecular weight of 485.56 g/mol. Its IUPAC name is 4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one.
Molecular Properties
| Compound Name | 4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one |
| PubChem CID | 177204421 |
| Molecular Formula | C22H34F3N7O2 |
| Molecular Weight | 485.56 g/mol |
| Exact Mass | 485.27 |
| IUPAC Name | 4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one |
| SMILES | CN1CCN(C2CC(Nc3ncc(C(F)(F)F)c(NCCCN4CCOCCC4=O)n3)C2)CC1 |
| InChI | InChI=1S/C22H34F3N7O2/c1-30-6-8-31(9-7-30)17-13-16(14-17)28-21-27-15-18(22(23,24)25)20(29-21)26-4-2-5-32-10-12-34-11-3-19(32)33/h15-17H,2-14H2,1H3,(H2,26,27,28,29) |
| InChIKey | PTZZXTIICGUISU-UHFFFAOYSA-N |
| XLogP | 1.74 |
| TPSA | 85.86 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 8 |
| Rotatable Bonds | 8 |
| Heavy Atoms | 34 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 485.56 |
| LogP ≤ 5 | 1.74 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 8 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one?
The IUPAC name of 4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one (CID 177204421) is 4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one.
What is the SMILES notation for 4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one?
The canonical SMILES for 4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one is CN1CCN(C2CC(Nc3ncc(C(F)(F)F)c(NCCCN4CCOCCC4=O)n3)C2)CC1.
What is the InChIKey of 4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one?
The InChIKey is PTZZXTIICGUISU-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H34F3N7O2/c1-30-6-8-31(9-7-30)17-13-16(14-17)28-21-27-15-18(22(23,24)25)20(29-21)26-4-2-5-32-10-12-34-11-3-19(32)33/h15-17H,2-14H2,1H3,(H2,26,27,28,29).
What are the key properties of 4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one?
4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one has a molecular weight of 485.56 g/mol, XLogP of 1.74, 8 rotatable bonds, 2 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[3-[[2-[[3-(4-methylpiperazin-1-yl)cyclobutyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]propyl]-1,4-oxazepan-5-one is sourced from PubChem (CID 177204421), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).