2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine

C13H12F2N2O2 — CID 178073329

IUPAC2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine
SMILESCOc1cc(C)ccc1-c1cnc(OC(F)F)cn1
InChIInChI=1S/C13H12F2N2O2/c1-8-3-4-9(11(5-8)18-2)10-6-17-12(7-16-10)19-13(14)15/h3-7,13H,1-2H3
InChIKeyAJGVPLWUGUWWBH-UHFFFAOYSA-N
MW266.25 g/mol
LogP3.06
Rot. Bonds4

About 2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine

2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine (PubChem CID 178073329) has the molecular formula C13H12F2N2O2 and a molecular weight of 266.25 g/mol. Its IUPAC name is 2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine.

Molecular Properties

Compound Name2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine
PubChem CID178073329
Molecular FormulaC13H12F2N2O2
Molecular Weight266.25 g/mol
Exact Mass266.09
IUPAC Name2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine
SMILESCOc1cc(C)ccc1-c1cnc(OC(F)F)cn1
InChIInChI=1S/C13H12F2N2O2/c1-8-3-4-9(11(5-8)18-2)10-6-17-12(7-16-10)19-13(14)15/h3-7,13H,1-2H3
InChIKeyAJGVPLWUGUWWBH-UHFFFAOYSA-N
XLogP3.06
TPSA44.24 Ų
H-Bond Donors
H-Bond Acceptors4
Rotatable Bonds4
Heavy Atoms19
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500266.25
LogP ≤ 53.06
H-Bond Donors ≤ 50
H-Bond Acceptors ≤ 104

Analyze 2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

2-(difluoromethoxy)-5-[2-(difluoromethoxy)-4-fluorophenyl]pyrazine
CID 178073304
3-bromo-4-[5-(difluoromethoxy)pyrazin-2-yl]-7-methyl-1H-indole
CID 178073123
2-(2-methoxy-4-methylphenyl)-5-pentylpyridine
CID 57131697
(1R)-1-[2-(2-methoxy-4-methylphenyl)-4-methylpyrimidin-5-yl]ethanamine
CID 106793249
7-chloro-4-[5-(difluoromethoxy)pyrazin-2-yl]-1H-indazole
CID 178073465
(1S)-1-[2-(2-methoxy-4-methylphenyl)-4-methylpyrimidin-5-yl]ethanol
CID 106793259
6-chloro-3-[5-(difluoromethoxy)pyrazin-2-yl]-2-fluorophenol
CID 178073095
4-[5-(difluoromethoxy)pyrazin-2-yl]-7-fluoro-1,3-dihydrobenzimidazole-2-thione
CID 178073534
3-bromo-4-[5-(difluoromethoxy)pyrazin-2-yl]-7-fluoro-1H-indole
CID 178072913
2-(2,3-difluoro-4-methoxyphenyl)-5-methylpyridine
CID 19910946
1-[2-(2-methoxy-4-methylphenyl)-4-methylpyrimidin-5-yl]ethanone
CID 106793219
2-(difluoromethoxy)-4-methylpyridine;ethane
CID 157031932

Frequently Asked Questions

What is the IUPAC name of 2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine?
The IUPAC name of 2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine (CID 178073329) is 2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine.
What is the SMILES notation for 2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine?
The canonical SMILES for 2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine is COc1cc(C)ccc1-c1cnc(OC(F)F)cn1.
What is the InChIKey of 2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine?
The InChIKey is AJGVPLWUGUWWBH-UHFFFAOYSA-N. The full InChI is InChI=1S/C13H12F2N2O2/c1-8-3-4-9(11(5-8)18-2)10-6-17-12(7-16-10)19-13(14)15/h3-7,13H,1-2H3.
What are the key properties of 2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine?
2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine has a molecular weight of 266.25 g/mol, XLogP of 3.06, 4 rotatable bonds, 0 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(difluoromethoxy)-5-(2-methoxy-4-methylphenyl)pyrazine is sourced from PubChem (CID 178073329), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).