About (2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one
(2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one (PubChem CID 178127360) has the molecular formula C15H16F3N5O3
and a molecular weight of 371.32 g/mol. Its IUPAC name is (2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one.
Molecular Properties
| Compound Name | (2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one |
| PubChem CID | 178127360 |
| Molecular Formula | C15H16F3N5O3 |
| Molecular Weight | 371.32 g/mol |
| Exact Mass | 371.12 |
| IUPAC Name | (2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one |
| SMILES | Cc1ncc(-c2cc(N[C@H](C)C(=O)N3CC(OC(F)(F)F)C3)ncn2)o1 |
| InChI | InChI=1S/C15H16F3N5O3/c1-8(14(24)23-5-10(6-23)26-15(16,17)18)22-13-3-11(20-7-21-13)12-4-19-9(2)25-12/h3-4,7-8,10H,5-6H2,1-2H3,(H,20,21,22)/t8-/m1/s1 |
| InChIKey | NBXRJHDTWYITGI-MRVPVSSYSA-N |
| XLogP | 1.99 |
| TPSA | 93.38 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 26 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 371.32 |
| LogP ≤ 5 | 1.99 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 7 |
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Frequently Asked Questions
What is the IUPAC name of (2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one?
The IUPAC name of (2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one (CID 178127360) is (2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one.
What is the SMILES notation for (2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one?
The canonical SMILES for (2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one is Cc1ncc(-c2cc(N[C@H](C)C(=O)N3CC(OC(F)(F)F)C3)ncn2)o1.
What is the InChIKey of (2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one?
The InChIKey is NBXRJHDTWYITGI-MRVPVSSYSA-N. The full InChI is InChI=1S/C15H16F3N5O3/c1-8(14(24)23-5-10(6-23)26-15(16,17)18)22-13-3-11(20-7-21-13)12-4-19-9(2)25-12/h3-4,7-8,10H,5-6H2,1-2H3,(H,20,21,22)/t8-/m1/s1.
What are the key properties of (2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one?
(2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one has a molecular weight of 371.32 g/mol, XLogP of 1.99, 5 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for (2R)-2-[[6-(2-methyl-1,3-oxazol-5-yl)pyrimidin-4-yl]amino]-1-[3-(trifluoromethoxy)azetidin-1-yl]propan-1-one is sourced from PubChem (CID 178127360), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).