About 2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one
2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one (PubChem CID 178136607) has the molecular formula C25H34N4O4S
and a molecular weight of 486.64 g/mol. Its IUPAC name is 2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one.
Molecular Properties
| Compound Name | 2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one |
| PubChem CID | 178136607 |
| Molecular Formula | C25H34N4O4S |
| Molecular Weight | 486.64 g/mol |
| Exact Mass | 486.23 |
| IUPAC Name | 2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one |
| SMILES | CCn1c(CN2Cc3ccc(C4CC4)cc3C2)ncc(OCC2CCN(S(C)(=O)=O)CC2)c1=O |
| InChI | InChI=1S/C25H34N4O4S/c1-3-29-24(16-27-14-21-7-6-20(19-4-5-19)12-22(21)15-27)26-13-23(25(29)30)33-17-18-8-10-28(11-9-18)34(2,31)32/h6-7,12-13,18-19H,3-5,8-11,14-17H2,1-2H3 |
| InChIKey | DRPHMMDJWOFQDK-UHFFFAOYSA-N |
| XLogP | 2.71 |
| TPSA | 84.74 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Heavy Atoms | 34 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 486.64 |
| LogP ≤ 5 | 2.71 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 7 |
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Frequently Asked Questions
What is the IUPAC name of 2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one?
The IUPAC name of 2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one (CID 178136607) is 2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one.
What is the SMILES notation for 2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one?
The canonical SMILES for 2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one is CCn1c(CN2Cc3ccc(C4CC4)cc3C2)ncc(OCC2CCN(S(C)(=O)=O)CC2)c1=O.
What is the InChIKey of 2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one?
The InChIKey is DRPHMMDJWOFQDK-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H34N4O4S/c1-3-29-24(16-27-14-21-7-6-20(19-4-5-19)12-22(21)15-27)26-13-23(25(29)30)33-17-18-8-10-28(11-9-18)34(2,31)32/h6-7,12-13,18-19H,3-5,8-11,14-17H2,1-2H3.
What are the key properties of 2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one?
2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one has a molecular weight of 486.64 g/mol, XLogP of 2.71, 8 rotatable bonds, 0 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[(5-cyclopropyl-1,3-dihydroisoindol-2-yl)methyl]-3-ethyl-5-[(1-methylsulfonylpiperidin-4-yl)methoxy]pyrimidin-4-one is sourced from PubChem (CID 178136607), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).