About 2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid
2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid (PubChem CID 18453663) has the molecular formula C18H14ClF2NO5S
and a molecular weight of 429.83 g/mol. Its IUPAC name is 2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid.
Molecular Properties
| Compound Name | 2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid |
| PubChem CID | 18453663 |
| Molecular Formula | C18H14ClF2NO5S |
| Molecular Weight | 429.83 g/mol |
| Exact Mass | 429.02 |
| IUPAC Name | 2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid |
| SMILES | COc1cc2c(CC(=O)O)c(C)n(C(=O)c3csc(OC(F)F)c3)c2cc1Cl |
| InChI | InChI=1S/C18H14ClF2NO5S/c1-8-10(5-15(23)24)11-4-14(26-2)12(19)6-13(11)22(8)17(25)9-3-16(28-7-9)27-18(20)21/h3-4,6-7,18H,5H2,1-2H3,(H,23,24) |
| InChIKey | YJTBREKURKDVDU-UHFFFAOYSA-N |
| XLogP | 4.59 |
| TPSA | 77.76 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 28 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 429.83 |
| LogP ≤ 5 | 4.59 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of 2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid?
The IUPAC name of 2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid (CID 18453663) is 2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid.
What is the SMILES notation for 2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid?
The canonical SMILES for 2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid is COc1cc2c(CC(=O)O)c(C)n(C(=O)c3csc(OC(F)F)c3)c2cc1Cl.
What is the InChIKey of 2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid?
The InChIKey is YJTBREKURKDVDU-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H14ClF2NO5S/c1-8-10(5-15(23)24)11-4-14(26-2)12(19)6-13(11)22(8)17(25)9-3-16(28-7-9)27-18(20)21/h3-4,6-7,18H,5H2,1-2H3,(H,23,24).
What are the key properties of 2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid?
2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid has a molecular weight of 429.83 g/mol, XLogP of 4.59, 6 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[6-chloro-1-[5-(difluoromethoxy)thiophene-3-carbonyl]-5-methoxy-2-methylindol-3-yl]acetic acid is sourced from PubChem (CID 18453663), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).