About N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide
N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide (PubChem CID 18516847) has the molecular formula C22H20FN5O
and a molecular weight of 389.43 g/mol. Its IUPAC name is N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide.
Molecular Properties
| Compound Name | N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide |
| PubChem CID | 18516847 |
| Molecular Formula | C22H20FN5O |
| Molecular Weight | 389.43 g/mol |
| Exact Mass | 389.17 |
| IUPAC Name | N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide |
| SMILES | CC(=O)NC(C)(C)c1ccc(-c2nc(Nc3ccc(F)cc3)ncc2C#N)cc1 |
| InChI | InChI=1S/C22H20FN5O/c1-14(29)28-22(2,3)17-6-4-15(5-7-17)20-16(12-24)13-25-21(27-20)26-19-10-8-18(23)9-11-19/h4-11,13H,1-3H3,(H,28,29)(H,25,26,27) |
| InChIKey | KULYECZXOSJQQD-UHFFFAOYSA-N |
| XLogP | 4.27 |
| TPSA | 90.70 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 29 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 389.43 |
| LogP ≤ 5 | 4.27 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 5 |
Analyze N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide with MolForge
Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.
Launch Full Analysis
Frequently Asked Questions
What is the IUPAC name of N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide?
The IUPAC name of N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide (CID 18516847) is N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide.
What is the SMILES notation for N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide?
The canonical SMILES for N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide is CC(=O)NC(C)(C)c1ccc(-c2nc(Nc3ccc(F)cc3)ncc2C#N)cc1.
What is the InChIKey of N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide?
The InChIKey is KULYECZXOSJQQD-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H20FN5O/c1-14(29)28-22(2,3)17-6-4-15(5-7-17)20-16(12-24)13-25-21(27-20)26-19-10-8-18(23)9-11-19/h4-11,13H,1-3H3,(H,28,29)(H,25,26,27).
What are the key properties of N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide?
N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide has a molecular weight of 389.43 g/mol, XLogP of 4.27, 5 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for N-[2-[4-[5-cyano-2-(4-fluoroanilino)pyrimidin-4-yl]phenyl]propan-2-yl]acetamide is sourced from PubChem (CID 18516847), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).