About 5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole
5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole (PubChem CID 20601454) has the molecular formula C20H15F3N4O2S2
and a molecular weight of 464.49 g/mol. Its IUPAC name is 5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole.
Molecular Properties
| Compound Name | 5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole |
| PubChem CID | 20601454 |
| Molecular Formula | C20H15F3N4O2S2 |
| Molecular Weight | 464.49 g/mol |
| Exact Mass | 464.06 |
| IUPAC Name | 5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole |
| SMILES | Cc1scnc1-c1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(C)(=O)=O)cn2)cc1 |
| InChI | InChI=1S/C20H15F3N4O2S2/c1-12-19(25-11-30-12)14-5-3-13(4-6-14)16-9-17(20(21,22)23)26-27(16)18-8-7-15(10-24-18)31(2,28)29/h3-11H,1-2H3 |
| InChIKey | RJDSGKQETJPZIH-UHFFFAOYSA-N |
| XLogP | 4.79 |
| TPSA | 77.74 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 31 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 464.49 |
| LogP ≤ 5 | 4.79 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 7 |
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Frequently Asked Questions
What is the IUPAC name of 5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole?
The IUPAC name of 5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole (CID 20601454) is 5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole.
What is the SMILES notation for 5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole?
The canonical SMILES for 5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole is Cc1scnc1-c1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(C)(=O)=O)cn2)cc1.
What is the InChIKey of 5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole?
The InChIKey is RJDSGKQETJPZIH-UHFFFAOYSA-N. The full InChI is InChI=1S/C20H15F3N4O2S2/c1-12-19(25-11-30-12)14-5-3-13(4-6-14)16-9-17(20(21,22)23)26-27(16)18-8-7-15(10-24-18)31(2,28)29/h3-11H,1-2H3.
What are the key properties of 5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole?
5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole has a molecular weight of 464.49 g/mol, XLogP of 4.79, 4 rotatable bonds, 0 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 5-methyl-4-[4-[1-(5-methylsulfonyl-2-pyridinyl)-3-(trifluoromethyl)pyrazol-5-yl]phenyl]-1,3-thiazole is sourced from PubChem (CID 20601454), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).