About 1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine
1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine (PubChem CID 20947579) has the molecular formula C19H21FN4O2S2
and a molecular weight of 420.54 g/mol. Its IUPAC name is 1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine.
Molecular Properties
| Compound Name | 1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine |
| PubChem CID | 20947579 |
| Molecular Formula | C19H21FN4O2S2 |
| Molecular Weight | 420.54 g/mol |
| Exact Mass | 420.11 |
| IUPAC Name | 1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine |
| SMILES | Cc1[nH]nc(-c2ccc(S(=O)(=O)N3CCN(c4ccc(F)cc4)CC3)s2)c1C |
| InChI | InChI=1S/C19H21FN4O2S2/c1-13-14(2)21-22-19(13)17-7-8-18(27-17)28(25,26)24-11-9-23(10-12-24)16-5-3-15(20)4-6-16/h3-8H,9-12H2,1-2H3,(H,21,22) |
| InChIKey | WIEJPHNEYSZNGM-UHFFFAOYSA-N |
| XLogP | 3.41 |
| TPSA | 69.30 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 28 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 420.54 |
| LogP ≤ 5 | 3.41 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 5 |
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Frequently Asked Questions
What is the IUPAC name of 1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine?
The IUPAC name of 1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine (CID 20947579) is 1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine.
What is the SMILES notation for 1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine?
The canonical SMILES for 1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine is Cc1[nH]nc(-c2ccc(S(=O)(=O)N3CCN(c4ccc(F)cc4)CC3)s2)c1C.
What is the InChIKey of 1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine?
The InChIKey is WIEJPHNEYSZNGM-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H21FN4O2S2/c1-13-14(2)21-22-19(13)17-7-8-18(27-17)28(25,26)24-11-9-23(10-12-24)16-5-3-15(20)4-6-16/h3-8H,9-12H2,1-2H3,(H,21,22).
What are the key properties of 1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine?
1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine has a molecular weight of 420.54 g/mol, XLogP of 3.41, 4 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 1-[5-(4,5-dimethyl-1H-pyrazol-3-yl)thiophen-2-yl]sulfonyl-4-(4-fluorophenyl)piperazine is sourced from PubChem (CID 20947579), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).