2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole

C19H11ClFN5S — CID 22032279

IUPAC2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole
SMILESFc1ccc(-c2[nH]ncc2-c2cc(Cl)c3ncc(-c4nccs4)n3c2)cc1
InChIInChI=1S/C19H11ClFN5S/c20-15-7-12(10-26-16(9-23-18(15)26)19-22-5-6-27-19)14-8-24-25-17(14)11-1-3-13(21)4-2-11/h1-10H,(H,24,25)
InChIKeyQOSRATNPUINJDE-UHFFFAOYSA-N
MW395.85 g/mol
LogP5.31
Rot. Bonds3

About 2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole

2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole (PubChem CID 22032279) has the molecular formula C19H11ClFN5S and a molecular weight of 395.85 g/mol. Its IUPAC name is 2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole.

Molecular Properties

Compound Name2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole
PubChem CID22032279
Molecular FormulaC19H11ClFN5S
Molecular Weight395.85 g/mol
Exact Mass395.04
IUPAC Name2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole
SMILESFc1ccc(-c2[nH]ncc2-c2cc(Cl)c3ncc(-c4nccs4)n3c2)cc1
InChIInChI=1S/C19H11ClFN5S/c20-15-7-12(10-26-16(9-23-18(15)26)19-22-5-6-27-19)14-8-24-25-17(14)11-1-3-13(21)4-2-11/h1-10H,(H,24,25)
InChIKeyQOSRATNPUINJDE-UHFFFAOYSA-N
XLogP5.31
TPSA58.87 Ų
H-Bond Donors1
H-Bond Acceptors5
Rotatable Bonds3
Heavy Atoms27
Complexity—

Lipinski Rule of Five

1 violation

RuleValue
MW ≤ 500395.85
LogP ≤ 55.31
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 105

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Related Compounds

1-(2-Fluorobenzyl)-4-(2-thiazolyl)-1H-pyrazolo[3,4-d]pyrimidine-6-amine
CID 22015509
N-[6-(2-chlorophenyl)sulfanyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine
CID 25094211
N-[6-(4-fluorophenyl)sulfanyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl]-3-methyl-1,2-thiazol-5-amine
CID 25094283
3-[5-(3-Chlorophenyl)thiophen-2-yl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine
CID 164612637
3-[5-(4-Fluorophenyl)thiophen-2-yl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine
CID 164616414
3-[5-(4-Chlorophenyl)thiophen-2-yl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine
CID 164620855
3-[5-(3-Fluorophenyl)thiophen-2-yl]-7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine
CID 164627013
2-[7-[[2-(3-Fluoro-2-pyridinyl)imidazol-1-yl]methyl]-8-propyl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl]-1,3-thiazole
CID 11293063
7-(4-Fluorophenyl)-8-[imidazo[1,2-a]pyridin-6-yl]-2-[(2-methyl-1,3-thiazol-4-yl)methyl]-[1,2,4] triazolo[1,5-c]pyrimidin-5-amine
CID 146490680
3-[5-(4-Chlorophenyl)thiophen-2-yl]-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine
CID 164619923
3-[5-(4-Fluorophenyl)thiophen-2-yl]-6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine
CID 164622607
6-(4-Chlorophenyl)-5-[1-(pyridin-2-ylmethyl)triazol-4-yl]imidazo[2,1-b][1,3]thiazole
CID 155255012

Frequently Asked Questions

What is the IUPAC name of 2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole?
The IUPAC name of 2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole (CID 22032279) is 2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole.
What is the SMILES notation for 2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole?
The canonical SMILES for 2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole is Fc1ccc(-c2[nH]ncc2-c2cc(Cl)c3ncc(-c4nccs4)n3c2)cc1.
What is the InChIKey of 2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole?
The InChIKey is QOSRATNPUINJDE-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H11ClFN5S/c20-15-7-12(10-26-16(9-23-18(15)26)19-22-5-6-27-19)14-8-24-25-17(14)11-1-3-13(21)4-2-11/h1-10H,(H,24,25).
What are the key properties of 2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole?
2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole has a molecular weight of 395.85 g/mol, XLogP of 5.31, 3 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[8-chloro-6-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]imidazo[1,2-a]pyridin-3-yl]-1,3-thiazole is sourced from PubChem (CID 22032279), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).