About N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide
N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide (PubChem CID 22243289) has the molecular formula C13H14F4N4O
and a molecular weight of 318.27 g/mol. Its IUPAC name is N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide.
Molecular Properties
| Compound Name | N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide |
| PubChem CID | 22243289 |
| Molecular Formula | C13H14F4N4O |
| Molecular Weight | 318.27 g/mol |
| Exact Mass | 318.11 |
| IUPAC Name | N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide |
| SMILES | O=C(NC1CN2CCC1CC2)c1ncc(C(F)(F)F)c(F)n1 |
| InChI | InChI=1S/C13H14F4N4O/c14-10-8(13(15,16)17)5-18-11(20-10)12(22)19-9-6-21-3-1-7(9)2-4-21/h5,7,9H,1-4,6H2,(H,19,22) |
| InChIKey | JHNVGXJDKDSLSP-UHFFFAOYSA-N |
| XLogP | 1.46 |
| TPSA | 58.12 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Heavy Atoms | 22 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 318.27 |
| LogP ≤ 5 | 1.46 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
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Frequently Asked Questions
What is the IUPAC name of N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide?
The IUPAC name of N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide (CID 22243289) is N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide.
What is the SMILES notation for N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide?
The canonical SMILES for N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide is O=C(NC1CN2CCC1CC2)c1ncc(C(F)(F)F)c(F)n1.
What is the InChIKey of N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide?
The InChIKey is JHNVGXJDKDSLSP-UHFFFAOYSA-N. The full InChI is InChI=1S/C13H14F4N4O/c14-10-8(13(15,16)17)5-18-11(20-10)12(22)19-9-6-21-3-1-7(9)2-4-21/h5,7,9H,1-4,6H2,(H,19,22).
What are the key properties of N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide?
N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide has a molecular weight of 318.27 g/mol, XLogP of 1.46, 2 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for N-(1-azabicyclo[2.2.2]octan-3-yl)-4-fluoro-5-(trifluoromethyl)pyrimidine-2-carboxamide is sourced from PubChem (CID 22243289), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).