About 1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide
1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide (PubChem CID 24597666) has the molecular formula C18H15ClF3N3OS2
and a molecular weight of 445.92 g/mol. Its IUPAC name is 1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide.
Molecular Properties
| Compound Name | 1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide |
| PubChem CID | 24597666 |
| Molecular Formula | C18H15ClF3N3OS2 |
| Molecular Weight | 445.92 g/mol |
| Exact Mass | 445.03 |
| IUPAC Name | 1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide |
| SMILES | O=C(NCCSCc1ccsc1)c1cnn(-c2ccc(Cl)cc2)c1C(F)(F)F |
| InChI | InChI=1S/C18H15ClF3N3OS2/c19-13-1-3-14(4-2-13)25-16(18(20,21)22)15(9-24-25)17(26)23-6-8-28-11-12-5-7-27-10-12/h1-5,7,9-10H,6,8,11H2,(H,23,26) |
| InChIKey | MMADCVJFAHGVEK-UHFFFAOYSA-N |
| XLogP | 5.27 |
| TPSA | 46.92 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Heavy Atoms | 28 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 445.92 |
| LogP ≤ 5 | 5.27 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Aliphatic_long_chain', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide?
The IUPAC name of 1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide (CID 24597666) is 1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide.
What is the SMILES notation for 1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide?
The canonical SMILES for 1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide is O=C(NCCSCc1ccsc1)c1cnn(-c2ccc(Cl)cc2)c1C(F)(F)F.
What is the InChIKey of 1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide?
The InChIKey is MMADCVJFAHGVEK-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H15ClF3N3OS2/c19-13-1-3-14(4-2-13)25-16(18(20,21)22)15(9-24-25)17(26)23-6-8-28-11-12-5-7-27-10-12/h1-5,7,9-10H,6,8,11H2,(H,23,26).
What are the key properties of 1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide?
1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide has a molecular weight of 445.92 g/mol, XLogP of 5.27, 7 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 1-(4-chlorophenyl)-N-[2-(thiophen-3-ylmethylsulfanyl)ethyl]-5-(trifluoromethyl)pyrazole-4-carboxamide is sourced from PubChem (CID 24597666), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).