About 6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one
6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one (PubChem CID 24999618) has the molecular formula C23H23ClFN3O3
and a molecular weight of 443.91 g/mol. Its IUPAC name is 6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one.
Molecular Properties
| Compound Name | 6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one |
| PubChem CID | 24999618 |
| Molecular Formula | C23H23ClFN3O3 |
| Molecular Weight | 443.91 g/mol |
| Exact Mass | 443.14 |
| IUPAC Name | 6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one |
| SMILES | N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(Oc2cc3cc[nH]c(=O)c3cc2Cl)CC1 |
| InChI | InChI=1S/C23H23ClFN3O3/c24-19-13-18-15(5-8-27-22(18)29)12-21(19)31-17-6-9-28(10-7-17)23(30)20(26)11-14-1-3-16(25)4-2-14/h1-5,8,12-13,17,20H,6-7,9-11,26H2,(H,27,29)/t20-/m0/s1 |
| InChIKey | KTGRAWHYOJDCGI-FQEVSTJZSA-N |
| XLogP | 3.26 |
| TPSA | 88.42 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 31 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 443.91 |
| LogP ≤ 5 | 3.26 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 4 |
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Frequently Asked Questions
What is the IUPAC name of 6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one?
The IUPAC name of 6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one (CID 24999618) is 6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one.
What is the SMILES notation for 6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one?
The canonical SMILES for 6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one is N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(Oc2cc3cc[nH]c(=O)c3cc2Cl)CC1.
What is the InChIKey of 6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one?
The InChIKey is KTGRAWHYOJDCGI-FQEVSTJZSA-N. The full InChI is InChI=1S/C23H23ClFN3O3/c24-19-13-18-15(5-8-27-22(18)29)12-21(19)31-17-6-9-28(10-7-17)23(30)20(26)11-14-1-3-16(25)4-2-14/h1-5,8,12-13,17,20H,6-7,9-11,26H2,(H,27,29)/t20-/m0/s1.
What are the key properties of 6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one?
6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one has a molecular weight of 443.91 g/mol, XLogP of 3.26, 5 rotatable bonds, 2 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[1-[(2S)-2-amino-3-(4-fluorophenyl)propanoyl]piperidin-4-yl]oxy-7-chloro-2H-isoquinolin-1-one is sourced from PubChem (CID 24999618), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).