About (5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione
(5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione (PubChem CID 25185441) has the molecular formula C19H11F6NO3S
and a molecular weight of 447.36 g/mol. Its IUPAC name is (5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione.
Molecular Properties
| Compound Name | (5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione |
| PubChem CID | 25185441 |
| Molecular Formula | C19H11F6NO3S |
| Molecular Weight | 447.36 g/mol |
| Exact Mass | 447.04 |
| IUPAC Name | (5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione |
| SMILES | O=C1S/C(=C\c2cccc(C(F)(F)F)c2)C(=O)N1Cc1ccc(OC(F)(F)F)cc1 |
| InChI | InChI=1S/C19H11F6NO3S/c20-18(21,22)13-3-1-2-12(8-13)9-15-16(27)26(17(28)30-15)10-11-4-6-14(7-5-11)29-19(23,24)25/h1-9H,10H2/b15-9- |
| InChIKey | IZDAXLSKLAFJRU-DHDCSXOGSA-N |
| XLogP | 5.84 |
| TPSA | 46.61 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 30 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 447.36 |
| LogP ≤ 5 | 5.84 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}, {'alert_name': 'thioester', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of (5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione?
The IUPAC name of (5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione (CID 25185441) is (5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione.
What is the SMILES notation for (5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione?
The canonical SMILES for (5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione is O=C1S/C(=C\c2cccc(C(F)(F)F)c2)C(=O)N1Cc1ccc(OC(F)(F)F)cc1.
What is the InChIKey of (5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione?
The InChIKey is IZDAXLSKLAFJRU-DHDCSXOGSA-N. The full InChI is InChI=1S/C19H11F6NO3S/c20-18(21,22)13-3-1-2-12(8-13)9-15-16(27)26(17(28)30-15)10-11-4-6-14(7-5-11)29-19(23,24)25/h1-9H,10H2/b15-9-.
What are the key properties of (5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione?
(5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione has a molecular weight of 447.36 g/mol, XLogP of 5.84, 4 rotatable bonds, 0 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for (5Z)-3-[[4-(trifluoromethoxy)phenyl]methyl]-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione is sourced from PubChem (CID 25185441), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).