About methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate
methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate (PubChem CID 2809149) has the molecular formula C21H19F3N4O3S
and a molecular weight of 464.47 g/mol. Its IUPAC name is methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate.
Molecular Properties
| Compound Name | methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate |
| PubChem CID | 2809149 |
| Molecular Formula | C21H19F3N4O3S |
| Molecular Weight | 464.47 g/mol |
| Exact Mass | 464.11 |
| IUPAC Name | methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate |
| SMILES | COC(=O)c1csc2c(C(F)(F)F)cc(N3CCN(C(=O)Nc4ccccc4)CC3)nc12 |
| InChI | InChI=1S/C21H19F3N4O3S/c1-31-19(29)14-12-32-18-15(21(22,23)24)11-16(26-17(14)18)27-7-9-28(10-8-27)20(30)25-13-5-3-2-4-6-13/h2-6,11-12H,7-10H2,1H3,(H,25,30) |
| InChIKey | CVCPEEQDIWFESJ-UHFFFAOYSA-N |
| XLogP | 4.46 |
| TPSA | 74.77 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 32 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 464.47 |
| LogP ≤ 5 | 4.46 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate?
The IUPAC name of methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate (CID 2809149) is methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate.
What is the SMILES notation for methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate?
The canonical SMILES for methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate is COC(=O)c1csc2c(C(F)(F)F)cc(N3CCN(C(=O)Nc4ccccc4)CC3)nc12.
What is the InChIKey of methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate?
The InChIKey is CVCPEEQDIWFESJ-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H19F3N4O3S/c1-31-19(29)14-12-32-18-15(21(22,23)24)11-16(26-17(14)18)27-7-9-28(10-8-27)20(30)25-13-5-3-2-4-6-13/h2-6,11-12H,7-10H2,1H3,(H,25,30).
What are the key properties of methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate?
methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate has a molecular weight of 464.47 g/mol, XLogP of 4.46, 3 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for methyl 5-[4-(phenylcarbamoyl)piperazin-1-yl]-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxylate is sourced from PubChem (CID 2809149), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).