About 3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide
3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide (PubChem CID 45183539) has the molecular formula C25H28FN5O2
and a molecular weight of 449.53 g/mol. Its IUPAC name is 3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide.
Molecular Properties
| Compound Name | 3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide |
| PubChem CID | 45183539 |
| Molecular Formula | C25H28FN5O2 |
| Molecular Weight | 449.53 g/mol |
| Exact Mass | 449.22 |
| IUPAC Name | 3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide |
| SMILES | O=C(NCC1CCC2(CCN(Cc3cccn3-c3ncccn3)CC2)O1)c1cccc(F)c1 |
| InChI | InChI=1S/C25H28FN5O2/c26-20-5-1-4-19(16-20)23(32)29-17-22-7-8-25(33-22)9-14-30(15-10-25)18-21-6-2-13-31(21)24-27-11-3-12-28-24/h1-6,11-13,16,22H,7-10,14-15,17-18H2,(H,29,32) |
| InChIKey | HWZCLCZVFKYOHO-UHFFFAOYSA-N |
| XLogP | 3.35 |
| TPSA | 72.28 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 33 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 449.53 |
| LogP ≤ 5 | 3.35 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 6 |
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Frequently Asked Questions
What is the IUPAC name of 3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide?
The IUPAC name of 3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide (CID 45183539) is 3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide.
What is the SMILES notation for 3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide?
The canonical SMILES for 3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide is O=C(NCC1CCC2(CCN(Cc3cccn3-c3ncccn3)CC2)O1)c1cccc(F)c1.
What is the InChIKey of 3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide?
The InChIKey is HWZCLCZVFKYOHO-UHFFFAOYSA-N. The full InChI is InChI=1S/C25H28FN5O2/c26-20-5-1-4-19(16-20)23(32)29-17-22-7-8-25(33-22)9-14-30(15-10-25)18-21-6-2-13-31(21)24-27-11-3-12-28-24/h1-6,11-13,16,22H,7-10,14-15,17-18H2,(H,29,32).
What are the key properties of 3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide?
3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide has a molecular weight of 449.53 g/mol, XLogP of 3.35, 6 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 3-fluoro-N-[[8-[(1-pyrimidin-2-ylpyrrol-2-yl)methyl]-1-oxa-8-azaspiro[4.5]decan-2-yl]methyl]benzamide is sourced from PubChem (CID 45183539), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).