N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide

C18H18F2N4OS — CID 46842485

IUPACN-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide
SMILESNC1CCCC(F)(F)C1NC(=O)c1cc(-c2cnc3ccccn23)cs1
InChIInChI=1S/C18H18F2N4OS/c19-18(20)6-3-4-12(21)16(18)23-17(25)14-8-11(10-26-14)13-9-22-15-5-1-2-7-24(13)15/h1-2,5,7-10,12,16H,3-4,6,21H2,(H,23,25)
InChIKeyKFMRAHNQSWXTEG-UHFFFAOYSA-N
MW376.43 g/mol
LogP3.31
Rot. Bonds3

About N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide

N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide (PubChem CID 46842485) has the molecular formula C18H18F2N4OS and a molecular weight of 376.43 g/mol. Its IUPAC name is N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide.

Molecular Properties

Compound NameN-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide
PubChem CID46842485
Molecular FormulaC18H18F2N4OS
Molecular Weight376.43 g/mol
Exact Mass376.12
IUPAC NameN-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide
SMILESNC1CCCC(F)(F)C1NC(=O)c1cc(-c2cnc3ccccn23)cs1
InChIInChI=1S/C18H18F2N4OS/c19-18(20)6-3-4-12(21)16(18)23-17(25)14-8-11(10-26-14)13-9-22-15-5-1-2-7-24(13)15/h1-2,5,7-10,12,16H,3-4,6,21H2,(H,23,25)
InChIKeyKFMRAHNQSWXTEG-UHFFFAOYSA-N
XLogP3.31
TPSA72.42 Ų
H-Bond Donors2
H-Bond Acceptors5
Rotatable Bonds3
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500376.43
LogP ≤ 53.31
H-Bond Donors ≤ 52
H-Bond Acceptors ≤ 105

Analyze N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-yl-5-methylthiophene-2-carboxamide
CID 46842486
N-[(1S,2R)-2-aminocyclopentyl]-4-imidazo[1,2-b]pyridazin-3-ylthiophene-2-carboxamide
CID 67123066
N-[(1R,6S)-6-amino-2,2-difluorocyclohexyl]-4-(difluoromethyl)-3-imidazo[1,2-b]pyridazin-3-ylcyclopenta-1,3-diene-1-carboxamide
CID 162561573
N-[(1R,6S)-6-amino-2,2-difluorocyclohexyl]-5-methyl-4-pyrazolo[1,5-a]pyridin-3-yl-1,3-thiazole-2-carboxamide
CID 58385870
N-(6-amino-2-fluoro-2-methylcyclohexyl)-5-ethyl-4-imidazo[1,2-b]pyridazin-3-ylthiophene-2-carboxamide
CID 91481298
N-(6-amino-2,2-difluorocyclohexyl)-4-(5-aminopyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole-2-carboxamide
CID 91441255
N-[(1R,6S)-6-amino-2,2-difluorocyclohexyl]-5-prop-1-en-2-yl-4-pyrazolo[1,5-a]pyridin-3-yl-1,3-thiazole-2-carboxamide
CID 58385932
N-[(1R,6S)-6-amino-2,2-difluorocyclohexyl]-4-(5-chloro-4-fluoropyrazolo[1,5-a]pyridin-3-yl)-1,3-thiazole-2-carboxamide
CID 67352973
N-[(1R,6R)-6-amino-2,2-difluorocyclohexyl]-5-(2-cyclopropylethynyl)-4-pyrazolo[1,5-a]pyridin-3-yl-1,3-thiazole-2-carboxamide
CID 58385875
N-[(1R,6S)-6-amino-2,2-difluorocyclohexyl]-5-chloro-4-[2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]-1,3-thiazole-2-carboxamide
CID 87367007
N-(6-amino-2,2-difluorocyclohexyl)-4-but-1-enyl-5-pyrazolo[1,5-a]pyridin-3-yl-3H-pyrrole-2-carboxamide
CID 91181312
N-[(1R,6R)-6-amino-2,2-difluorocyclohexyl]-4-(6-chloropyrazolo[1,5-a]pyridin-3-yl)-5-methyl-1,3-thiazole-2-carboxamide
CID 67349719

Frequently Asked Questions

What is the IUPAC name of N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide?
The IUPAC name of N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide (CID 46842485) is N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide.
What is the SMILES notation for N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide?
The canonical SMILES for N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide is NC1CCCC(F)(F)C1NC(=O)c1cc(-c2cnc3ccccn23)cs1.
What is the InChIKey of N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide?
The InChIKey is KFMRAHNQSWXTEG-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H18F2N4OS/c19-18(20)6-3-4-12(21)16(18)23-17(25)14-8-11(10-26-14)13-9-22-15-5-1-2-7-24(13)15/h1-2,5,7-10,12,16H,3-4,6,21H2,(H,23,25).
What are the key properties of N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide?
N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide has a molecular weight of 376.43 g/mol, XLogP of 3.31, 3 rotatable bonds, 2 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for N-(6-amino-2,2-difluorocyclohexyl)-4-imidazo[1,2-a]pyridin-3-ylthiophene-2-carboxamide is sourced from PubChem (CID 46842485), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).