About N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide
N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide (PubChem CID 46917450) has the molecular formula C19H23F3N2O5S
and a molecular weight of 448.46 g/mol. Its IUPAC name is N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide.
Molecular Properties
| Compound Name | N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide |
| PubChem CID | 46917450 |
| Molecular Formula | C19H23F3N2O5S |
| Molecular Weight | 448.46 g/mol |
| Exact Mass | 448.13 |
| IUPAC Name | N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide |
| SMILES | COC(C(=O)NCC1CC1)=C1CCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1 |
| InChI | InChI=1S/C19H23F3N2O5S/c1-28-17(18(25)23-12-13-2-3-13)14-8-10-24(11-9-14)30(26,27)16-6-4-15(5-7-16)29-19(20,21)22/h4-7,13H,2-3,8-12H2,1H3,(H,23,25) |
| InChIKey | KPULJPMYNOEPEE-UHFFFAOYSA-N |
| XLogP | 2.80 |
| TPSA | 84.94 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Heavy Atoms | 30 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 448.46 |
| LogP ≤ 5 | 2.80 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'acyclic_C=C-O', 'substructure': 'N/A'}, {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'} |
|---|
Analyze N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide with MolForge
Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.
Launch Full Analysis
Frequently Asked Questions
What is the IUPAC name of N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide?
The IUPAC name of N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide (CID 46917450) is N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide.
What is the SMILES notation for N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide?
The canonical SMILES for N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide is COC(C(=O)NCC1CC1)=C1CCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)CC1.
What is the InChIKey of N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide?
The InChIKey is KPULJPMYNOEPEE-UHFFFAOYSA-N. The full InChI is InChI=1S/C19H23F3N2O5S/c1-28-17(18(25)23-12-13-2-3-13)14-8-10-24(11-9-14)30(26,27)16-6-4-15(5-7-16)29-19(20,21)22/h4-7,13H,2-3,8-12H2,1H3,(H,23,25).
What are the key properties of N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide?
N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide has a molecular weight of 448.46 g/mol, XLogP of 2.80, 7 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for N-(cyclopropylmethyl)-2-methoxy-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-4-ylidene]acetamide is sourced from PubChem (CID 46917450), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).