About (2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide
(2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide (PubChem CID 46917525) has the molecular formula C18H21F3N2O4S
and a molecular weight of 418.44 g/mol. Its IUPAC name is (2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide.
Molecular Properties
| Compound Name | (2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide |
| PubChem CID | 46917525 |
| Molecular Formula | C18H21F3N2O4S |
| Molecular Weight | 418.44 g/mol |
| Exact Mass | 418.12 |
| IUPAC Name | (2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide |
| SMILES | O=C(/C=C1\CCCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)C1)NCC1CC1 |
| InChI | InChI=1S/C18H21F3N2O4S/c19-18(20,21)27-15-5-7-16(8-6-15)28(25,26)23-9-1-2-14(12-23)10-17(24)22-11-13-3-4-13/h5-8,10,13H,1-4,9,11-12H2,(H,22,24)/b14-10+ |
| InChIKey | PFWUWXHUEBHRDQ-GXDHUFHOSA-N |
| XLogP | 2.82 |
| TPSA | 75.71 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 28 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 418.44 |
| LogP ≤ 5 | 2.82 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'} |
|---|
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Frequently Asked Questions
What is the IUPAC name of (2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide?
The IUPAC name of (2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide (CID 46917525) is (2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide.
What is the SMILES notation for (2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide?
The canonical SMILES for (2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide is O=C(/C=C1\CCCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)C1)NCC1CC1.
What is the InChIKey of (2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide?
The InChIKey is PFWUWXHUEBHRDQ-GXDHUFHOSA-N. The full InChI is InChI=1S/C18H21F3N2O4S/c19-18(20,21)27-15-5-7-16(8-6-15)28(25,26)23-9-1-2-14(12-23)10-17(24)22-11-13-3-4-13/h5-8,10,13H,1-4,9,11-12H2,(H,22,24)/b14-10+.
What are the key properties of (2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide?
(2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide has a molecular weight of 418.44 g/mol, XLogP of 2.82, 6 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for (2E)-N-(cyclopropylmethyl)-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide is sourced from PubChem (CID 46917525), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).