About (2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide
(2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide (PubChem CID 46917526) has the molecular formula C17H19F3N2O4S
and a molecular weight of 404.41 g/mol. Its IUPAC name is (2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide.
Molecular Properties
| Compound Name | (2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide |
| PubChem CID | 46917526 |
| Molecular Formula | C17H19F3N2O4S |
| Molecular Weight | 404.41 g/mol |
| Exact Mass | 404.10 |
| IUPAC Name | (2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide |
| SMILES | O=C(/C=C1\CCCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)C1)NC1CC1 |
| InChI | InChI=1S/C17H19F3N2O4S/c18-17(19,20)26-14-5-7-15(8-6-14)27(24,25)22-9-1-2-12(11-22)10-16(23)21-13-3-4-13/h5-8,10,13H,1-4,9,11H2,(H,21,23)/b12-10+ |
| InChIKey | YTJSPBIPXQHDGC-ZRDIBKRKSA-N |
| XLogP | 2.57 |
| TPSA | 75.71 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 27 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 404.41 |
| LogP ≤ 5 | 2.57 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of (2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide?
The IUPAC name of (2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide (CID 46917526) is (2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide.
What is the SMILES notation for (2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide?
The canonical SMILES for (2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide is O=C(/C=C1\CCCN(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)C1)NC1CC1.
What is the InChIKey of (2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide?
The InChIKey is YTJSPBIPXQHDGC-ZRDIBKRKSA-N. The full InChI is InChI=1S/C17H19F3N2O4S/c18-17(19,20)26-14-5-7-15(8-6-14)27(24,25)22-9-1-2-12(11-22)10-16(23)21-13-3-4-13/h5-8,10,13H,1-4,9,11H2,(H,21,23)/b12-10+.
What are the key properties of (2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide?
(2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide has a molecular weight of 404.41 g/mol, XLogP of 2.57, 5 rotatable bonds, 1 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for (2E)-N-cyclopropyl-2-[1-[4-(trifluoromethoxy)phenyl]sulfonylpiperidin-3-ylidene]acetamide is sourced from PubChem (CID 46917526), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).