About 9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one
9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one (PubChem CID 50939737) has the molecular formula C19H11Cl2F3N3O3S+
and a molecular weight of 489.28 g/mol. Its IUPAC name is 9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one.
Molecular Properties
| Compound Name | 9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one |
| PubChem CID | 50939737 |
| Molecular Formula | C19H11Cl2F3N3O3S+ |
| Molecular Weight | 489.28 g/mol |
| Exact Mass | 487.98 |
| IUPAC Name | 9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one |
| SMILES | O=c1c(-c2cccc(OC(F)(F)F)c2)c(O)[n+](Cc2cnc(Cl)s2)c2c(Cl)cccn12 |
| InChI | InChI=1S/C19H10Cl2F3N3O3S/c20-13-5-2-6-26-15(13)27(9-12-8-25-18(21)31-12)17(29)14(16(26)28)10-3-1-4-11(7-10)30-19(22,23)24/h1-8H,9H2/p+1 |
| InChIKey | JUTSHUSLSXZGMK-UHFFFAOYSA-O |
| XLogP | 4.67 |
| TPSA | 67.71 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 31 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 489.28 |
| LogP ≤ 5 | 4.67 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 6 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'quaternary_nitrogen_1', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one?
The IUPAC name of 9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one (CID 50939737) is 9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one.
What is the SMILES notation for 9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one?
The canonical SMILES for 9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one is O=c1c(-c2cccc(OC(F)(F)F)c2)c(O)[n+](Cc2cnc(Cl)s2)c2c(Cl)cccn12.
What is the InChIKey of 9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one?
The InChIKey is JUTSHUSLSXZGMK-UHFFFAOYSA-O. The full InChI is InChI=1S/C19H10Cl2F3N3O3S/c20-13-5-2-6-26-15(13)27(9-12-8-25-18(21)31-12)17(29)14(16(26)28)10-3-1-4-11(7-10)30-19(22,23)24/h1-8H,9H2/p+1.
What are the key properties of 9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one?
9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one has a molecular weight of 489.28 g/mol, XLogP of 4.67, 4 rotatable bonds, 1 hydrogen bond donors, and 6 hydrogen bond acceptors.
Where does this data come from?
All data for 9-chloro-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-hydroxy-3-[3-(trifluoromethoxy)phenyl]pyrido[1,2-a]pyrimidin-1-ium-4-one is sourced from PubChem (CID 50939737), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).