About 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide
4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide (PubChem CID 53257137) has the molecular formula C17H17ClF3N5OS
and a molecular weight of 431.87 g/mol. Its IUPAC name is 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide.
Molecular Properties
| Compound Name | 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide |
| PubChem CID | 53257137 |
| Molecular Formula | C17H17ClF3N5OS |
| Molecular Weight | 431.87 g/mol |
| Exact Mass | 431.08 |
| IUPAC Name | 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide |
| SMILES | COc1cccc(NC(=S)N2CCN(c3ncc(C(F)(F)F)cc3Cl)CC2)n1 |
| InChI | InChI=1S/C17H17ClF3N5OS/c1-27-14-4-2-3-13(23-14)24-16(28)26-7-5-25(6-8-26)15-12(18)9-11(10-22-15)17(19,20)21/h2-4,9-10H,5-8H2,1H3,(H,23,24,28) |
| InChIKey | XEJVOHJPABBJEE-UHFFFAOYSA-N |
| XLogP | 3.68 |
| TPSA | 53.52 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Heavy Atoms | 28 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 431.87 |
| LogP ≤ 5 | 3.68 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 5 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Thiocarbonyl_group', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide?
The IUPAC name of 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide (CID 53257137) is 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide.
What is the SMILES notation for 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide?
The canonical SMILES for 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide is COc1cccc(NC(=S)N2CCN(c3ncc(C(F)(F)F)cc3Cl)CC2)n1.
What is the InChIKey of 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide?
The InChIKey is XEJVOHJPABBJEE-UHFFFAOYSA-N. The full InChI is InChI=1S/C17H17ClF3N5OS/c1-27-14-4-2-3-13(23-14)24-16(28)26-7-5-25(6-8-26)15-12(18)9-11(10-22-15)17(19,20)21/h2-4,9-10H,5-8H2,1H3,(H,23,24,28).
What are the key properties of 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide?
4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide has a molecular weight of 431.87 g/mol, XLogP of 3.68, 3 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-N-(6-methoxy-2-pyridinyl)piperazine-1-carbothioamide is sourced from PubChem (CID 53257137), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).