About N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide
N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide (PubChem CID 53261931) has the molecular formula C21H21Cl2F3N2O
and a molecular weight of 445.31 g/mol. Its IUPAC name is N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide.
Molecular Properties
| Compound Name | N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide |
| PubChem CID | 53261931 |
| Molecular Formula | C21H21Cl2F3N2O |
| Molecular Weight | 445.31 g/mol |
| Exact Mass | 444.10 |
| IUPAC Name | N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide |
| SMILES | CC(=O)NC(C)c1ccc(N2CCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1 |
| InChI | InChI=1S/C21H21Cl2F3N2O/c1-13(27-14(2)29)15-3-5-19(6-4-15)28-8-7-20(12-28,21(24,25)26)16-9-17(22)11-18(23)10-16/h3-6,9-11,13H,7-8,12H2,1-2H3,(H,27,29) |
| InChIKey | XKNMEJYWLGWFPI-UHFFFAOYSA-N |
| XLogP | 5.90 |
| TPSA | 32.34 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 29 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 445.31 |
| LogP ≤ 5 | 5.90 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 2 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'anil_di_alk_E(186)', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide?
The IUPAC name of N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide (CID 53261931) is N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide.
What is the SMILES notation for N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide?
The canonical SMILES for N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide is CC(=O)NC(C)c1ccc(N2CCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1.
What is the InChIKey of N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide?
The InChIKey is XKNMEJYWLGWFPI-UHFFFAOYSA-N. The full InChI is InChI=1S/C21H21Cl2F3N2O/c1-13(27-14(2)29)15-3-5-19(6-4-15)28-8-7-20(12-28,21(24,25)26)16-9-17(22)11-18(23)10-16/h3-6,9-11,13H,7-8,12H2,1-2H3,(H,27,29).
What are the key properties of N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide?
N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide has a molecular weight of 445.31 g/mol, XLogP of 5.90, 4 rotatable bonds, 1 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]acetamide is sourced from PubChem (CID 53261931), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).