About N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide
N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide (PubChem CID 53261995) has the molecular formula C22H23Cl2F3N2O
and a molecular weight of 459.34 g/mol. Its IUPAC name is N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide.
Molecular Properties
| Compound Name | N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide |
| PubChem CID | 53261995 |
| Molecular Formula | C22H23Cl2F3N2O |
| Molecular Weight | 459.34 g/mol |
| Exact Mass | 458.11 |
| IUPAC Name | N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide |
| SMILES | CCC(=O)NC(C)c1ccc(N2CCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1 |
| InChI | InChI=1S/C22H23Cl2F3N2O/c1-3-20(30)28-14(2)15-4-6-19(7-5-15)29-9-8-21(13-29,22(25,26)27)16-10-17(23)12-18(24)11-16/h4-7,10-12,14H,3,8-9,13H2,1-2H3,(H,28,30) |
| InChIKey | JDLNJUCACIFVMW-UHFFFAOYSA-N |
| XLogP | 6.29 |
| TPSA | 32.34 Ų |
| H-Bond Donors | 1 |
| H-Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Heavy Atoms | 30 |
| Complexity | — |
Lipinski Rule of Five
1 violation
| Rule | Value |
| MW ≤ 500 | 459.34 |
| LogP ≤ 5 | 6.29 |
| H-Bond Donors ≤ 5 | 1 |
| H-Bond Acceptors ≤ 10 | 2 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'anil_di_alk_E(186)', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide?
The IUPAC name of N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide (CID 53261995) is N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide.
What is the SMILES notation for N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide?
The canonical SMILES for N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide is CCC(=O)NC(C)c1ccc(N2CCC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)cc1.
What is the InChIKey of N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide?
The InChIKey is JDLNJUCACIFVMW-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H23Cl2F3N2O/c1-3-20(30)28-14(2)15-4-6-19(7-5-15)29-9-8-21(13-29,22(25,26)27)16-10-17(23)12-18(24)11-16/h4-7,10-12,14H,3,8-9,13H2,1-2H3,(H,28,30).
What are the key properties of N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide?
N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide has a molecular weight of 459.34 g/mol, XLogP of 6.29, 5 rotatable bonds, 1 hydrogen bond donors, and 2 hydrogen bond acceptors.
Where does this data come from?
All data for N-[1-[4-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)pyrrolidin-1-yl]phenyl]ethyl]propanamide is sourced from PubChem (CID 53261995), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).