About 4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one
4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one (PubChem CID 53311997) has the molecular formula C18H17FN6O2
and a molecular weight of 368.37 g/mol. Its IUPAC name is 4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one.
Molecular Properties
| Compound Name | 4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one |
| PubChem CID | 53311997 |
| Molecular Formula | C18H17FN6O2 |
| Molecular Weight | 368.37 g/mol |
| Exact Mass | 368.14 |
| IUPAC Name | 4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one |
| SMILES | Cc1ccnc(Nc2ccc(F)c(-c3cnc(N4CCNC(=O)C4)o3)n2)c1 |
| InChI | InChI=1S/C18H17FN6O2/c1-11-4-5-20-15(8-11)23-14-3-2-12(19)17(24-14)13-9-22-18(27-13)25-7-6-21-16(26)10-25/h2-5,8-9H,6-7,10H2,1H3,(H,21,26)(H,20,23,24) |
| InChIKey | AAHWZHLLMILLEN-UHFFFAOYSA-N |
| XLogP | 2.26 |
| TPSA | 96.18 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 27 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 368.37 |
| LogP ≤ 5 | 2.26 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 7 |
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Frequently Asked Questions
What is the IUPAC name of 4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one?
The IUPAC name of 4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one (CID 53311997) is 4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one.
What is the SMILES notation for 4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one?
The canonical SMILES for 4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one is Cc1ccnc(Nc2ccc(F)c(-c3cnc(N4CCNC(=O)C4)o3)n2)c1.
What is the InChIKey of 4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one?
The InChIKey is AAHWZHLLMILLEN-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H17FN6O2/c1-11-4-5-20-15(8-11)23-14-3-2-12(19)17(24-14)13-9-22-18(27-13)25-7-6-21-16(26)10-25/h2-5,8-9H,6-7,10H2,1H3,(H,21,26)(H,20,23,24).
What are the key properties of 4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one?
4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one has a molecular weight of 368.37 g/mol, XLogP of 2.26, 4 rotatable bonds, 2 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 4-[5-[3-fluoro-6-[(4-methyl-2-pyridinyl)amino]-2-pyridinyl]-1,3-oxazol-2-yl]piperazin-2-one is sourced from PubChem (CID 53311997), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).