About 2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid
2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid (PubChem CID 5348572) has the molecular formula C18H14N4O6S
and a molecular weight of 414.40 g/mol. Its IUPAC name is 2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid.
Molecular Properties
| Compound Name | 2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid |
| PubChem CID | 5348572 |
| Molecular Formula | C18H14N4O6S |
| Molecular Weight | 414.40 g/mol |
| Exact Mass | 414.06 |
| IUPAC Name | 2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid |
| SMILES | O=C(O)CC1S/C(=N/N=C/c2ccc([N+](=O)[O-])cc2)N(c2ccc(O)cc2)C1=O |
| InChI | InChI=1S/C18H14N4O6S/c23-14-7-5-12(6-8-14)21-17(26)15(9-16(24)25)29-18(21)20-19-10-11-1-3-13(4-2-11)22(27)28/h1-8,10,15,23H,9H2,(H,24,25)/b19-10+,20-18+ |
| InChIKey | VKOHOWTVNACYHL-GQVLRKDXSA-N |
| XLogP | 2.61 |
| TPSA | 145.70 Ų |
| H-Bond Donors | 2 |
| H-Bond Acceptors | 8 |
| Rotatable Bonds | 6 |
| Heavy Atoms | 29 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 414.40 |
| LogP ≤ 5 | 2.61 |
| H-Bond Donors ≤ 5 | 2 |
| H-Bond Acceptors ≤ 10 | 8 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'imine_1', 'substructure': 'N/A'}, {'alert_name': 'nitro_group', 'substructure': 'N/A'}, {'alert_name': 'Oxygen-nitrogen_single_bond', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid?
The IUPAC name of 2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid (CID 5348572) is 2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid.
What is the SMILES notation for 2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid?
The canonical SMILES for 2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid is O=C(O)CC1S/C(=N/N=C/c2ccc([N+](=O)[O-])cc2)N(c2ccc(O)cc2)C1=O.
What is the InChIKey of 2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid?
The InChIKey is VKOHOWTVNACYHL-GQVLRKDXSA-N. The full InChI is InChI=1S/C18H14N4O6S/c23-14-7-5-12(6-8-14)21-17(26)15(9-16(24)25)29-18(21)20-19-10-11-1-3-13(4-2-11)22(27)28/h1-8,10,15,23H,9H2,(H,24,25)/b19-10+,20-18+.
What are the key properties of 2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid?
2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid has a molecular weight of 414.40 g/mol, XLogP of 2.61, 6 rotatable bonds, 2 hydrogen bond donors, and 8 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[(2E)-3-(4-hydroxyphenyl)-2-[(E)-(4-nitrophenyl)methylidenehydrazinylidene]-4-oxo-1,3-thiazolidin-5-yl]acetic acid is sourced from PubChem (CID 5348572), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).