(4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate

C150H188N26O23 — CID 54328073

About (4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate

(4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate (PubChem CID 54328073) has the molecular formula C150H188N26O23 and a molecular weight of 2723.31 g/mol. Its IUPAC name is (4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate.

Molecular Properties

• Compound Name: (4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate
• PubChem CID: 54328073
• Molecular Formula: C150H188N26O23
• Molecular Weight: 2723.31 g/mol
• Exact Mass: 2721.43
• IUPAC Name: (4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate
• SMILES: [C-]#[N+]c1c(C(=O)OC2(C)C(C)(C)CCCC2(C)C)c2nc(C(C)CC)[nH]n2c1OC(=O)N(CC=C)CC=C.[C-]#[N+]c1c(C(=O)OC2C(C)CC(C)CC2C)c2nc(-c3ccc(C)cc3)[nH]n2c1OC(=O)N1CCOCC1.[C-]#[N+]c1c(C(=O)OC2C(C)CC(C)CC2C)c2nc(CC)[nH]n2c1OC(=O)Nc1ccccc1.[C-]#[N+]c1c(C(=O)OC2C(C)CC(CCCC)CC2C)c2nc(C(C)C)[nH]n2c1OC(=O)N(C)c1ccccc1.[C-]#[N+]c1c(C(=O)OC2C(C)CCCC2C)c2nc(-c3cccc(NC(=O)C(CC)Oc4ccc(C)cc4C)c3)[nH]n2c1OC(=O)N(CC)CC
• InChI: InChI=1S/C38H46N6O6.C30H39N5O4.C29H41N5O4.C28H33N5O5.C25H29N5O4/c1-9-28(48-29-19-18-22(4)20-25(29)7)35(45)40-27-17-13-16-26(21-27)33-41-34-30(37(46)49-32-23(5)14-12-15-24(32)6)31(39-8)36(44(34)42-33)50-38(47)43(10-2)11-3;1-8-9-13-21-16-19(4)25(20(5)17-21)38-29(36)23-24(31-6)28(35-27(23)32-26(33-35)18(2)3)39-30(37)34(7)22-14-11-10-12-15-22;1-11-17-33(18-12-2)26(36)37-24-21(30-10)20(23-31-22(19(4)13-3)32-34(23)24)25(35)38-29(9)27(5,6)15-14-16-28(29,7)8;1-16-6-8-20(9-7-16)24-30-25-21(27(34)37-23-18(3)14-17(2)15-19(23)4)22(29-5)26(33(25)31-24)38-28(35)32-10-12-36-13-11-32;1-6-18-28-22-19(24(31)33-21-15(3)12-14(2)13-16(21)4)20(26-5)23(30(22)29-18)34-25(32)27-17-10-8-7-9-11-17/h13,16-21,23-24,28,32H,9-12,14-15H2,1-7H3,(H,40,45)(H,41,42);10-12,14-15,18-21,25H,8-9,13,16-17H2,1-5,7H3,(H,32,33);11-12,19H,1-2,13-18H2,3-9H3,(H,31,32);6-9,17-19,23H,10-15H2,1-4H3,(H,30,31);7-11,14-16,21H,6,12-13H2,1-4H3,(H,27,32)(H,28,29)
• InChIKey: SWJJUBFSZJMDKX-UHFFFAOYSA-N
• XLogP: 33.40
• TPSA: 522.80 Ų
• H-Bond Donors: 7
• H-Bond Acceptors: 33
• Rotatable Bonds: 37
• Heavy Atoms: 199
• Complexity: —

Lipinski Rule of Five

4 violations

Rule	Value
MW ≤ 500	2723.31
LogP ≤ 5	33.40
H-Bond Donors ≤ 5	7
H-Bond Acceptors ≤ 10	33

Computed Properties (RDKit)

• Structural Alerts: {'alert_name': '>_2_ester_groups', 'substructure': 'N/A'}, {'alert_name': 'Carbo_cation/anion', 'substructure': 'N/A'}, {'alert_name': 'isolated_alkene', 'substructure': 'N/A'}

Frequently Asked Questions

What is the IUPAC name of (4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate?

The IUPAC name of (4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate (CID 54328073) is (4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate.

What is the SMILES notation for (4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate?

The canonical SMILES for (4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate is [C-]#[N+]c1c(C(=O)OC2(C)C(C)(C)CCCC2(C)C)c2nc(C(C)CC)[nH]n2c1OC(=O)N(CC=C)CC=C.[C-]#[N+]c1c(C(=O)OC2C(C)CC(C)CC2C)c2nc(-c3ccc(C)cc3)[nH]n2c1OC(=O)N1CCOCC1.[C-]#[N+]c1c(C(=O)OC2C(C)CC(C)CC2C)c2nc(CC)[nH]n2c1OC(=O)Nc1ccccc1.[C-]#[N+]c1c(C(=O)OC2C(C)CC(CCCC)CC2C)c2nc(C(C)C)[nH]n2c1OC(=O)N(C)c1ccccc1.[C-]#[N+]c1c(C(=O)OC2C(C)CCCC2C)c2nc(-c3cccc(NC(=O)C(CC)Oc4ccc(C)cc4C)c3)[nH]n2c1OC(=O)N(CC)CC.

What is the InChIKey of (4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate?

The InChIKey is SWJJUBFSZJMDKX-UHFFFAOYSA-N. The full InChI is InChI=1S/C38H46N6O6.C30H39N5O4.C29H41N5O4.C28H33N5O5.C25H29N5O4/c1-9-28(48-29-19-18-22(4)20-25(29)7)35(45)40-27-17-13-16-26(21-27)33-41-34-30(37(46)49-32-23(5)14-12-15-24(32)6)31(39-8)36(44(34)42-33)50-38(47)43(10-2)11-3;1-8-9-13-21-16-19(4)25(20(5)17-21)38-29(36)23-24(31-6)28(35-27(23)32-26(33-35)18(2)3)39-30(37)34(7)22-14-11-10-12-15-22;1-11-17-33(18-12-2)26(36)37-24-21(30-10)20(23-31-22(19(4)13-3)32-34(23)24)25(35)38-29(9)27(5,6)15-14-16-28(29,7)8;1-16-6-8-20(9-7-16)24-30-25-21(27(34)37-23-18(3)14-17(2)15-19(23)4)22(29-5)26(33(25)31-24)38-28(35)32-10-12-36-13-11-32;1-6-18-28-22-19(24(31)33-21-15(3)12-14(2)13-16(21)4)20(26-5)23(30(22)29-18)34-25(32)27-17-10-8-7-9-11-17/h13,16-21,23-24,28,32H,9-12,14-15H2,1-7H3,(H,40,45)(H,41,42);10-12,14-15,18-21,25H,8-9,13,16-17H2,1-5,7H3,(H,32,33);11-12,19H,1-2,13-18H2,3-9H3,(H,31,32);6-9,17-19,23H,10-15H2,1-4H3,(H,30,31);7-11,14-16,21H,6,12-13H2,1-4H3,(H,27,32)(H,28,29).

What are the key properties of (4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate?

(4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate has a molecular weight of 2723.31 g/mol, XLogP of 33.40, 37 rotatable bonds, 7 hydrogen bond donors, and 33 hydrogen bond acceptors.

Where does this data come from?

All data for (4-butyl-2,6-dimethylcyclohexyl) 6-isocyano-5-[methyl(phenyl)carbamoyl]oxy-2-propan-2-yl-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,6-dimethylcyclohexyl) 5-(diethylcarbamoyloxy)-2-[3-[2-(2,4-dimethylphenoxy)butanoylamino]phenyl]-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;[6-isocyano-2-(4-methylphenyl)-7-(2,4,6-trimethylcyclohexyl)oxycarbonyl-3H-pyrrolo[1,2-b][1,2,4]triazol-5-yl] morpholine-4-carboxylate;(1,2,2,6,6-pentamethylcyclohexyl) 5-[bis(prop-2-enyl)carbamoyloxy]-2-butan-2-yl-6-isocyano-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate;(2,4,6-trimethylcyclohexyl) 2-ethyl-6-isocyano-5-(phenylcarbamoyloxy)-3H-pyrrolo[1,2-b][1,2,4]triazole-7-carboxylate is sourced from PubChem (CID 54328073), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).