About 3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one
3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one (PubChem CID 54564021) has the molecular formula C22H19FN2O4
and a molecular weight of 394.40 g/mol. Its IUPAC name is 3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one.
Molecular Properties
| Compound Name | 3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one |
| PubChem CID | 54564021 |
| Molecular Formula | C22H19FN2O4 |
| Molecular Weight | 394.40 g/mol |
| Exact Mass | 394.13 |
| IUPAC Name | 3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one |
| SMILES | CC(=O)c1c[nH]c(C=C2C(=O)Nc3ccc(F)c(C#CC4(O)CCOCC4)c32)c1 |
| InChI | InChI=1S/C22H19FN2O4/c1-13(26)14-10-15(24-12-14)11-17-20-16(4-5-22(28)6-8-29-9-7-22)18(23)2-3-19(20)25-21(17)27/h2-3,10-12,24,28H,6-9H2,1H3,(H,25,27) |
| InChIKey | ZSORIJBCWYMUOI-UHFFFAOYSA-N |
| XLogP | 2.74 |
| TPSA | 91.42 Ų |
| H-Bond Donors | 3 |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Heavy Atoms | 29 |
| Complexity | — |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 394.40 |
| LogP ≤ 5 | 2.74 |
| H-Bond Donors ≤ 5 | 3 |
| H-Bond Acceptors ≤ 10 | 4 |
Computed Properties (RDKit)
| Structural Alerts | {'alert_name': 'Michael_acceptor_1', 'substructure': 'N/A'}, {'alert_name': 'triple_bond', 'substructure': 'N/A'} |
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Frequently Asked Questions
What is the IUPAC name of 3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one?
The IUPAC name of 3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one (CID 54564021) is 3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one.
What is the SMILES notation for 3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one?
The canonical SMILES for 3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one is CC(=O)c1c[nH]c(C=C2C(=O)Nc3ccc(F)c(C#CC4(O)CCOCC4)c32)c1.
What is the InChIKey of 3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one?
The InChIKey is ZSORIJBCWYMUOI-UHFFFAOYSA-N. The full InChI is InChI=1S/C22H19FN2O4/c1-13(26)14-10-15(24-12-14)11-17-20-16(4-5-22(28)6-8-29-9-7-22)18(23)2-3-19(20)25-21(17)27/h2-3,10-12,24,28H,6-9H2,1H3,(H,25,27).
What are the key properties of 3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one?
3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one has a molecular weight of 394.40 g/mol, XLogP of 2.74, 2 rotatable bonds, 3 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 3-[(4-acetyl-1H-pyrrol-2-yl)methylidene]-5-fluoro-4-[2-(4-hydroxyoxan-4-yl)ethynyl]-1H-indol-2-one is sourced from PubChem (CID 54564021), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).