2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide

C18H18ClF3N2O2 — CID 55525311

IUPAC2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide
SMILESO=C(COc1ccc(Cl)c2cccnc12)NC1CCCC(C(F)(F)F)C1
InChIInChI=1S/C18H18ClF3N2O2/c19-14-6-7-15(17-13(14)5-2-8-23-17)26-10-16(25)24-12-4-1-3-11(9-12)18(20,21)22/h2,5-8,11-12H,1,3-4,9-10H2,(H,24,25)
InChIKeyOOWDWMRTJDHYFD-UHFFFAOYSA-N
MW386.80 g/mol
LogP4.50
Rot. Bonds4

About 2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide

2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide (PubChem CID 55525311) has the molecular formula C18H18ClF3N2O2 and a molecular weight of 386.80 g/mol. Its IUPAC name is 2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide.

Molecular Properties

Compound Name2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide
PubChem CID55525311
Molecular FormulaC18H18ClF3N2O2
Molecular Weight386.80 g/mol
Exact Mass386.10
IUPAC Name2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide
SMILESO=C(COc1ccc(Cl)c2cccnc12)NC1CCCC(C(F)(F)F)C1
InChIInChI=1S/C18H18ClF3N2O2/c19-14-6-7-15(17-13(14)5-2-8-23-17)26-10-16(25)24-12-4-1-3-11(9-12)18(20,21)22/h2,5-8,11-12H,1,3-4,9-10H2,(H,24,25)
InChIKeyOOWDWMRTJDHYFD-UHFFFAOYSA-N
XLogP4.50
TPSA51.22 Ų
H-Bond Donors1
H-Bond Acceptors3
Rotatable Bonds4
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500386.80
LogP ≤ 54.50
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 103

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Related Compounds

2-(5-chloroquinolin-8-yl)oxy-N-piperidin-4-ylacetamide
CID 119386547
N-[2-(aminomethyl)cyclopentyl]-2-(5-chloroquinolin-8-yl)oxyacetamide
CID 119601328
2-(5-chloroquinolin-8-yl)oxy-N-[(4S)-3,4-dihydro-2H-thiochromen-4-yl]acetamide
CID 97016809
2-(5-chloroquinolin-8-yl)oxy-N-[[(1R,2S)-2-methylcyclohexyl]carbamoyl]acetamide
CID 8716448
2-(2-benzylphenoxy)-N-[3-(trifluoromethyl)cyclohexyl]acetamide
CID 18147791
methyl 2-(5-chloroquinolin-8-yl)oxyacetate
CID 15257198
2-naphthalen-2-yloxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide
CID 42883922
N-cyclooctyl-2-(5-nitroquinolin-8-yl)oxyacetamide
CID 23987661
N'-[2-(5-chloroquinolin-8-yl)oxyacetyl]benzohydrazide
CID 55602763
N-(5-chloro-2-fluorophenyl)-2-(5-chloroquinolin-8-yl)oxyacetamide
CID 8716254
2-(3-bromophenoxy)-N-[3-(trifluoromethyl)cyclohexyl]acetamide
CID 86918559
2-(5-chloroquinolin-8-yl)oxy-N-[(4-hydroxypyrrolidin-3-yl)methyl]acetamide
CID 120943944

Frequently Asked Questions

What is the IUPAC name of 2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide?
The IUPAC name of 2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide (CID 55525311) is 2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide.
What is the SMILES notation for 2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide?
The canonical SMILES for 2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide is O=C(COc1ccc(Cl)c2cccnc12)NC1CCCC(C(F)(F)F)C1.
What is the InChIKey of 2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide?
The InChIKey is OOWDWMRTJDHYFD-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H18ClF3N2O2/c19-14-6-7-15(17-13(14)5-2-8-23-17)26-10-16(25)24-12-4-1-3-11(9-12)18(20,21)22/h2,5-8,11-12H,1,3-4,9-10H2,(H,24,25).
What are the key properties of 2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide?
2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide has a molecular weight of 386.80 g/mol, XLogP of 4.50, 4 rotatable bonds, 1 hydrogen bond donors, and 3 hydrogen bond acceptors.
Where does this data come from?
All data for 2-(5-chloroquinolin-8-yl)oxy-N-[3-(trifluoromethyl)cyclohexyl]acetamide is sourced from PubChem (CID 55525311), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).