5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine

C21H20N6O — CID 56953275

IUPAC5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine
SMILESc1ccc([C@@H]2C[C@H]2COc2cc(NCc3cccnc3)n3nccc3n2)nc1
InChIInChI=1S/C21H20N6O/c1-2-8-23-18(5-1)17-10-16(17)14-28-21-11-20(27-19(26-21)6-9-25-27)24-13-15-4-3-7-22-12-15/h1-9,11-12,16-17,24H,10,13-14H2/t16-,17+/m0/s1
InChIKeyOSUJIHMHCRTTAY-DLBZAZTESA-N
MW372.43 g/mol
LogP3.31
Rot. Bonds7

About 5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine

5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine (PubChem CID 56953275) has the molecular formula C21H20N6O and a molecular weight of 372.43 g/mol. Its IUPAC name is 5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine.

Molecular Properties

Compound Name5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine
PubChem CID56953275
Molecular FormulaC21H20N6O
Molecular Weight372.43 g/mol
Exact Mass372.17
IUPAC Name5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine
SMILESc1ccc([C@@H]2C[C@H]2COc2cc(NCc3cccnc3)n3nccc3n2)nc1
InChIInChI=1S/C21H20N6O/c1-2-8-23-18(5-1)17-10-16(17)14-28-21-11-20(27-19(26-21)6-9-25-27)24-13-15-4-3-7-22-12-15/h1-9,11-12,16-17,24H,10,13-14H2/t16-,17+/m0/s1
InChIKeyOSUJIHMHCRTTAY-DLBZAZTESA-N
XLogP3.31
TPSA77.23 Ų
H-Bond Donors1
H-Bond Acceptors7
Rotatable Bonds7
Heavy Atoms28
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500372.43
LogP ≤ 53.31
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 107

Analyze 5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Related Compounds

N-[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]-5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]pyrazolo[1,5-a]pyrimidin-7-amine
CID 56952794
6-methyl-N-[(1-methylpyrazol-4-yl)methyl]-5-[[(1S,2S)-2-pyridin-2-ylcyclopropyl]methoxy]pyrazolo[1,5-a]pyrimidin-7-amine
CID 56953085
5-[[(1S,2S)-2-(6-methoxy-2-pyridinyl)cyclopropyl]methoxy]-N-[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]pyrazolo[1,5-a]pyrimidin-7-amine
CID 56952493
2-ethyl-N-[(1-methylpyrazol-4-yl)methyl]-6-[(2-pyridin-2-ylcyclopropyl)methoxy]pyrimidin-4-amine
CID 71272463
[3-bromo-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-5-yl]methanol;[7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-5-yl]methanol
CID 157262286
7-methyl-N-(pyridin-3-ylmethyl)-[1,2,4]triazolo[1,5-a]pyridin-5-amine
CID 43232785
3-bromo-5-N-cyclohexyl-7-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine
CID 21067210
5-(2-bicyclo[2.2.1]heptanyl)-3-bromo-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CID 21067044
3-bromo-5-(2-bromophenyl)-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CID 21066638
6-[(2-pyridin-2-ylcyclopropyl)methoxy]-2-(trifluoromethyl)pyrimidin-4-amine
CID 140649990
CID 88986825
CID 88986825
3-phenylmethoxy-5-[(1S,2S)-2-(pyridin-3-yloxymethyl)cyclopropyl]pyridine
CID 68612157

Frequently Asked Questions

What is the IUPAC name of 5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine?
The IUPAC name of 5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine (CID 56953275) is 5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine.
What is the SMILES notation for 5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine?
The canonical SMILES for 5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine is c1ccc([C@@H]2C[C@H]2COc2cc(NCc3cccnc3)n3nccc3n2)nc1.
What is the InChIKey of 5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine?
The InChIKey is OSUJIHMHCRTTAY-DLBZAZTESA-N. The full InChI is InChI=1S/C21H20N6O/c1-2-8-23-18(5-1)17-10-16(17)14-28-21-11-20(27-19(26-21)6-9-25-27)24-13-15-4-3-7-22-12-15/h1-9,11-12,16-17,24H,10,13-14H2/t16-,17+/m0/s1.
What are the key properties of 5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine?
5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine has a molecular weight of 372.43 g/mol, XLogP of 3.31, 7 rotatable bonds, 1 hydrogen bond donors, and 7 hydrogen bond acceptors.
Where does this data come from?
All data for 5-[[(1R,2R)-2-pyridin-2-ylcyclopropyl]methoxy]-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine is sourced from PubChem (CID 56953275), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).