N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide

C28H25F5N4O4S — CID 57400677

About N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide

N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide (PubChem CID 57400677) has the molecular formula C28H25F5N4O4S and a molecular weight of 608.59 g/mol. Its IUPAC name is N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide.

Molecular Properties

• Compound Name: N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide
• PubChem CID: 57400677
• Molecular Formula: C28H25F5N4O4S
• Molecular Weight: 608.59 g/mol
• Exact Mass: 608.15
• IUPAC Name: N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide
• SMILES: CCS(=O)(=O)CCN(C(=O)Cc1ccc(F)c(C(F)(F)F)c1)[C@H](C)c1nc2ncccc2c(=O)n1-c1ccc(F)cc1
• InChI: InChI=1S/C28H25F5N4O4S/c1-3-42(40,41)14-13-36(24(38)16-18-6-11-23(30)22(15-18)28(31,32)33)17(2)26-35-25-21(5-4-12-34-25)27(39)37(26)20-9-7-19(29)8-10-20/h4-12,15,17H,3,13-14,16H2,1-2H3/t17-/m1/s1
• InChIKey: HLRSJAFCIHUSTE-QGZVFWFLSA-N
• XLogP: 4.64
• TPSA: 102.23 Ų
• H-Bond Acceptors: 7
• Rotatable Bonds: 9
• Heavy Atoms: 42
• Complexity: —

Lipinski Rule of Five

1 violation

Rule	Value
MW ≤ 500	608.59
LogP ≤ 5	4.64
H-Bond Donors ≤ 5	0
H-Bond Acceptors ≤ 10	7

Frequently Asked Questions

What is the IUPAC name of N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide?

The IUPAC name of N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide (CID 57400677) is N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide.

What is the SMILES notation for N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide?

The canonical SMILES for N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide is CCS(=O)(=O)CCN(C(=O)Cc1ccc(F)c(C(F)(F)F)c1)[C@H](C)c1nc2ncccc2c(=O)n1-c1ccc(F)cc1.

What is the InChIKey of N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide?

The InChIKey is HLRSJAFCIHUSTE-QGZVFWFLSA-N. The full InChI is InChI=1S/C28H25F5N4O4S/c1-3-42(40,41)14-13-36(24(38)16-18-6-11-23(30)22(15-18)28(31,32)33)17(2)26-35-25-21(5-4-12-34-25)27(39)37(26)20-9-7-19(29)8-10-20/h4-12,15,17H,3,13-14,16H2,1-2H3/t17-/m1/s1.

What are the key properties of N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide?

N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide has a molecular weight of 608.59 g/mol, XLogP of 4.64, 9 rotatable bonds, 0 hydrogen bond donors, and 7 hydrogen bond acceptors.

Where does this data come from?

All data for N-(2-ethylsulfonylethyl)-N-[(1R)-1-[3-(4-fluorophenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide is sourced from PubChem (CID 57400677), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).