About 6-[1-(3,5-Difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one
6-[1-(3,5-Difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one (PubChem CID 58122408) has the molecular formula C27H29F2N3O
and a molecular weight of 449.50 g/mol. Its IUPAC name is 6-[1-(3,5-difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one.
Molecular Properties
| Compound Name | 6-[1-(3,5-Difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one |
| PubChem CID | 58122408 |
| Molecular Formula | C27H29F2N3O |
| Molecular Weight | 449.50 g/mol |
| Exact Mass | 449.23 |
| IUPAC Name | 6-[1-(3,5-difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one |
| SMILES | CC1=C(C=CC(=C1)C2CC3(C2)CCCN(C3=O)C(C)C4=CC(=CC(=C4)F)F)N5C=C(N=C5)C |
| InChI | InChI=1S/C27H29F2N3O/c1-17-9-20(5-6-25(17)31-15-18(2)30-16-31)22-13-27(14-22)7-4-8-32(26(27)33)19(3)21-10-23(28)12-24(29)11-21/h5-6,9-12,15-16,19,22H,4,7-8,13-14H2,1-3H3 |
| InChIKey | ADXFPXAXLIDOHP-UHFFFAOYSA-N |
| XLogP | 4.80 |
| TPSA | 38.10 Ų |
| H-Bond Donors | |
| H-Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Heavy Atoms | 33 |
| Complexity | 703 |
Lipinski Rule of Five
Passes Rule of Five
| Rule | Value |
| MW ≤ 500 | 449.50 |
| LogP ≤ 5 | 4.80 |
| H-Bond Donors ≤ 5 | 0 |
| H-Bond Acceptors ≤ 10 | 4 |
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Frequently Asked Questions
What is the IUPAC name of 6-[1-(3,5-Difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one?
The IUPAC name of 6-[1-(3,5-Difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one (CID 58122408) is 6-[1-(3,5-difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one.
What is the SMILES notation for 6-[1-(3,5-Difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one?
The canonical SMILES for 6-[1-(3,5-Difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one is CC1=C(C=CC(=C1)C2CC3(C2)CCCN(C3=O)C(C)C4=CC(=CC(=C4)F)F)N5C=C(N=C5)C.
What is the InChIKey of 6-[1-(3,5-Difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one?
The InChIKey is ADXFPXAXLIDOHP-UHFFFAOYSA-N. The full InChI is InChI=1S/C27H29F2N3O/c1-17-9-20(5-6-25(17)31-15-18(2)30-16-31)22-13-27(14-22)7-4-8-32(26(27)33)19(3)21-10-23(28)12-24(29)11-21/h5-6,9-12,15-16,19,22H,4,7-8,13-14H2,1-3H3.
What are the key properties of 6-[1-(3,5-Difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one?
6-[1-(3,5-Difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one has a molecular weight of 449.50 g/mol, XLogP of 4.80, 4 rotatable bonds, 0 hydrogen bond donors, and 4 hydrogen bond acceptors.
Where does this data come from?
All data for 6-[1-(3,5-Difluorophenyl)ethyl]-2-[3-methyl-4-(4-methylimidazol-1-yl)phenyl]-6-azaspiro[3.5]nonan-5-one is sourced from PubChem (CID 58122408), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).