2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide

C18H12F2N4OS — CID 58208487

IUPAC2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide
SMILESO=C(Nc1nccs1)c1cccn2cc(-c3ccc(C(F)F)cc3)nc12
InChIInChI=1S/C18H12F2N4OS/c19-15(20)12-5-3-11(4-6-12)14-10-24-8-1-2-13(16(24)22-14)17(25)23-18-21-7-9-26-18/h1-10,15H,(H,21,23,25)
InChIKeyZFKUMSMOCCAVDC-UHFFFAOYSA-N
MW370.38 g/mol
LogP4.65
Rot. Bonds4

About 2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide

2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide (PubChem CID 58208487) has the molecular formula C18H12F2N4OS and a molecular weight of 370.38 g/mol. Its IUPAC name is 2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide.

Molecular Properties

Compound Name2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide
PubChem CID58208487
Molecular FormulaC18H12F2N4OS
Molecular Weight370.38 g/mol
Exact Mass370.07
IUPAC Name2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide
SMILESO=C(Nc1nccs1)c1cccn2cc(-c3ccc(C(F)F)cc3)nc12
InChIInChI=1S/C18H12F2N4OS/c19-15(20)12-5-3-11(4-6-12)14-10-24-8-1-2-13(16(24)22-14)17(25)23-18-21-7-9-26-18/h1-10,15H,(H,21,23,25)
InChIKeyZFKUMSMOCCAVDC-UHFFFAOYSA-N
XLogP4.65
TPSA59.29 Ų
H-Bond Donors1
H-Bond Acceptors5
Rotatable Bonds4
Heavy Atoms26
Complexity—

Lipinski Rule of Five

Passes Rule of Five

RuleValue
MW ≤ 500370.38
LogP ≤ 54.65
H-Bond Donors ≤ 51
H-Bond Acceptors ≤ 105

Analyze 2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide with MolForge

Explore ADMET properties, 3D molecular structure, drug-likeness score, and discover similar compounds using our AI-powered platform.

Launch Full Analysis

Frequently Asked Questions

What is the IUPAC name of 2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide?
The IUPAC name of 2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide (CID 58208487) is 2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide.
What is the SMILES notation for 2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide?
The canonical SMILES for 2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide is O=C(Nc1nccs1)c1cccn2cc(-c3ccc(C(F)F)cc3)nc12.
What is the InChIKey of 2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide?
The InChIKey is ZFKUMSMOCCAVDC-UHFFFAOYSA-N. The full InChI is InChI=1S/C18H12F2N4OS/c19-15(20)12-5-3-11(4-6-12)14-10-24-8-1-2-13(16(24)22-14)17(25)23-18-21-7-9-26-18/h1-10,15H,(H,21,23,25).
What are the key properties of 2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide?
2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide has a molecular weight of 370.38 g/mol, XLogP of 4.65, 4 rotatable bonds, 1 hydrogen bond donors, and 5 hydrogen bond acceptors.
Where does this data come from?
All data for 2-[4-(difluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)imidazo[1,2-a]pyridine-8-carboxamide is sourced from PubChem (CID 58208487), the world's largest open chemistry database maintained by the National Library of Medicine (NIH).